ArticleBiophysical journal2012
pH wave-front propagation in the urea-urease reaction.
Article in Biophysical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Urea-Urease pH-Clock-Enabled Time-Lapse Thiol-Acrylate Adhesives: Two-Part Formulations and One-Pot Underwater Activation.ACS omega · 2026Article
- A Novel Approach to Cure-on-Demand Coatings Using Ammonia to Catalyze Thiol-Acrylate and Thiol-Epoxy Reactions.ACS omega · 2025Article
- Membrane Transport Modulates the pH-Regulated Feedback of an Enzyme Reaction Confined within Lipid Vesicles.ACS nano · 2025Article
- Chemical waves in reaction-diffusion networks of small organic molecules.Chemical science · 2025Article
- A Light Scattering Investigation of Enzymatic Gelation in Self-Assembling Peptides.Gels (Basel, Switzerland) · 2023Article
- Photoswitchable gating of non-equilibrium enzymatic feedback in chemically communicating polymersome nanoreactors.Nature chemistry · 2023Article
- Feedback and Communication in Active Hydrogel Spheres with pH Fronts: Facile Approaches to Grow Soft Hydrogel Structures.Angewandte Chemie (International ed. in English) · 2021Article
- Reaction-diffusion hydrogels from urease enzyme particles for patterned coatings.Communications chemistry · 2021Article
- Urea-Urease Reaction in Controlling Properties of Supramolecular Hydrogels: Pros and Cons.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021Review
- Non-equilibrium signal integration in hydrogels.Nature communications · 2020Article
- Immobilization adjusted clock reaction in the urea-urease-HRSC advances · 2019Article
- Switches induced by quorum sensing in a model of enzyme-loaded microparticles.Journal of the Royal Society, Interface · 2017Article
- Temporal Control of Gelation and Polymerization Fronts Driven by an Autocatalytic Enzyme Reaction.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2016Article
- Temporal Control of Gelation and Polymerization Fronts Driven by an Autocatalytic Enzyme Reaction.Angewandte Chemie (International ed. in English) · 2016Article
Corrections and comments
- Erratum issuedCarranzo, Arturo [corrected to Carranza, Arturo]
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The urease-catalyzed hydrolysis of urea displays feedback that results in a switch from acid (pH ~3) to base (pH ~9) after a controllable period of time (from 10 to >5000 s). Here we show that the spatially distributed reaction can support pH wave fronts propagating with a speed of the order of 0.1-1 mm min(-1). The experimental results were reproduced qualitatively in reaction-diffusion simulations including a Michaelis-Menten expression for the urease reaction with a bell-shaped rate-pH dependence. However, this model fails to predict that at lower enzyme concentrations, the unstirred reaction does not always support fronts when the well-stirred reaction still rapidly switches to high pH.
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