ArticleBiophysical journal2012
Quantitative analysis of amyloid-integrated biofilms formed by uropathogenic Escherichia coli at the air-liquid interface.
Article in Biophysical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 78 citations in OpenAlex.
- Diversification of biofilm architecture among freshwaterApplied and environmental microbiology · 2026Article
- Thermodynamics of Surfactant-Enriched Binary-Fluid Systems.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Article
- Socializing at the Air-Liquid Interface: a Functional Genomic Analysis on Biofilm-Related Genes during Pellicle Formation by Escherichia coli and Its Interaction with Aeromonas australiensis.Applied and environmental microbiology · 2023Article
- Ultra-lightweight living structural material for enhanced stiffness and environmental sensing.Materials today. Bio · 2023Article
- The CRISPR-Cas System Differentially Regulates Surface-Attached and Pellicle Biofilm in Salmonella enterica Serovar Typhimurium.Microbiology spectrum · 2022Article
- Non-pathogenic Escherichia coli biofilms: effects of growth conditions and surface properties on structure and curli gene expression.Archives of microbiology · 2020Article
- Growth of microorganisms in an interfacially driven space bioreactor analog.NPJ microgravity · 2020Article
- 3D bacterial cellulose biofilms formed by foam templating.NPJ biofilms and microbiomes · 2018Article
- Films of Bacteria at Interfaces (FBI): Remodeling of Fluid Interfaces by Pseudomonas aeruginosa.Scientific reports · 2017Article
- The Physiological and Pathological Implications of the Formation of Hydrogels, with a Specific Focus on Amyloid Polypeptides.Biomolecules · 2017Review
- Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology.Chemical Society reviews · 2017Review
- Adhesion mechanisms of curli subunit CsgA to abiotic surfaces.Science advances · 2016Article
- Methodologies for Studying B. subtilis Biofilms as a Model for Characterizing Small Molecule Biofilm Inhibitors.Journal of visualized experiments : JoVE · 2016Article
- Plasticity of Candida albicans Biofilms.Microbiology and molecular biology reviews : MMBR · 2016Review
- Dynamics of the formation of a hydrogel by a pathogenic amyloid peptide: islet amyloid polypeptide.Scientific reports · 2016Article
- New Weapons to Fight Old Enemies: Novel Strategies for the (Bio)control of Bacterial Biofilms in the Food Industry.Frontiers in microbiology · 2016Review
- Bacillus subtilis Bacteria Generate an Internal Mechanical Force within a Biofilm.Biophysical journal · 2015Article
- Bacterial floc mediated rapid streamer formation in creeping flows.Scientific reports · 2015Article
- The Biology of the Escherichia coli Extracellular Matrix.Microbiology spectrum · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Bacterial biofilms are complex multicellular assemblies, characterized by a heterogeneous extracellular polymeric matrix, that have emerged as hallmarks of persistent infectious diseases. New approaches and quantitative data are needed to elucidate the composition and architecture of biofilms, and such data need to be correlated with mechanical and physicochemical properties that relate to function. We performed a panel of interfacial rheological measurements during biofilm formation at the air-liquid interface by the Escherichia coli strain UTI89, which is noted for its importance in studies of urinary tract infection and for its assembly of functional amyloid fibers termed curli. Brewster-angle microscopy and measurements of the surface elasticity (G(s)') and stress-strain response provided sensitive and quantitative parameters that revealed distinct stages during bacterial colonization, aggregation, and eventual formation of a pellicle at the air-liquid interface. Pellicles that formed under conditions that upregulate curli production exhibited an increase in strength and viscoelastic properties as well as a greater ability to recover from stress-strain perturbation. The results suggest that curli, as hydrophobic extracellular amyloid fibers, enhance the strength, viscoelasticity, and resistance to strain of E. coli biofilms formed at the air-liquid interface.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.