Evidence map›Paper›PMID 22947585›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2012

Delayed antibiotic prescribing and associated antibiotic consumption in adults with acute cough.

Nick A Francis, David Gillespie, Jacqueline Nuttall, Kerenza Hood, Paul Little, Theo Verheij, Herman Goossens, Samuel Coenen, Christopher C Butler

Erratum issuedAbstract read
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Pooled it
  4. Trial
  5. Effects on antibiotic dispensing rates of interventions to promote delayed prescribing for respiratory tract infections in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2013
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  10. Post-consultation acute respiratory tract infection recovery: a latent class-informed analysis of individual patient data.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
    Article
  11. Implementation of the delayed antibiotic prescribing strategy. Prospective observation study in primary care.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2022
    Observational
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4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

9 authors.

Nick A FrancisCochrane Institute of Primary Care and Public Health, Cardiff University School of Medicine, Cardiff. francisna@cf.ac.uk
David Gillespie
Jacqueline Nuttall
Kerenza Hood
Paul Little
Theo Verheij
Herman Goossens
Samuel Coenen
Christopher C Butler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDelayed antibiotic prescribing is promoted as a strategy to reduce antibiotic consumption, but its use and its effect on antibiotic consumption in routine care is poorly described.

aimTo quantify delayed antibiotic prescribing in adults presenting in primary care with acute cough/lower respiratory tract infection (LRTI), duration of advised delay, consumption of delayed antibiotics, and factors associated with consumption. DESIGN AND

settingProspective observational cohort in general practices in 14 primary care networks in 13 European countries.

methodGPs recorded clinical features and antibiotic prescribing for adults presenting with an acute infective illness with cough as the dominant symptom. Patients recorded their consumption of antibiotics from any source during the 28-day follow up.

resultsTwo hundred and ten (6.3%) of 3368 patients with usable consultation data were prescribed delayed antibiotics. The median recommended delay period was 3 days. Seventy-five (44.4%) of the 169 with consumption data consumed the antibiotic course and a further 18 (10.7%) took another antibiotic during the study period. 50 (29.6%) started their delayed course on the day of prescription. Clinician diagnosis of upper respiratory tract/viral infection and clinician's perception of patient's wanting antibiotics were associated with less consumption of the delayed prescription. Patient's wanting antibiotics was associated with greater consumption.

conclusionDelayed antibiotic prescribing was used infrequently for adults presenting in general practice with acute cough/LRTI. When used, the effect on antibiotic consumption was less than found in most trials. There are opportunities for standardising the intervention and promoting wider uptake.

Indexed as

Acute DiseaseAdultAgedAnti-Bacterial AgentsCoughEuropeGeneral PracticeHumansMedication AdherenceMiddle AgedPractice Patterns, Physicians'Prospective StudiesRespiratory Tract InfectionsTime-to-TreatmentAnti-Bacterial Agents

Identifiers

PMID22947585
PMCPMC3426603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.