Evidence map›Paper›PMID 22946281›Full record

ReviewPediatric endocrinology reviews : PER2012

Cognition and behavior in Turner syndrome: a brief review.

D S Hong, A L Reiss

Abstract readReview
In one paragraph

Review in Pediatric endocrinology reviews : PER, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Profiling of Sexually Dimorphic Genes in Neural Cells to IdentifyFrontiers in cell and developmental biology · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Sex differences in psychiatric disorders: what we can learn from sex chromosome aneuploidies.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

D S HongCenter for Interdisciplinary Brain Sciences Research, Stanford University, Stanford, CA 94305, USA. dshong@stanford.edu
A L Reiss
Stanford University · US

Funding

NEUROPSYCHIATRIC-MOLECULAR ASSOCIATIONS IN FRAGILE X SYNR01MH050047 · NIMH · STANFORD UNIVERSITY · PI REISS, ALLAN L · 1993 to 2022
$12.5M
TRAINING FOR CHILD PSYCHIATRY AND CHILD DEVELOPMENTT32MH019908 · NIMH · STANFORD UNIVERSITY · PI IAN H GOTLIB, DAVID S HONG · 1993 to 2026
$6.3M
Gene, Brain and Behavior in Turner SyndromeR01HD049653 · NICHD · STANFORD UNIVERSITY · PI REISS, ALLAN L · 2006 to 2016
$6.0M
Neuroanatomical substrates of cognition in mosaic Turner syndromeK23MH097120 · NIMH · STANFORD UNIVERSITY · PI HONG, DAVID S · 2012 to 2015
$725k
NICHD NIH HHS HD049653NICHD NIH HHS R01 HD049653NIMH NIH HHS K23 MH097120NIMH NIH HHS MH050047NIMH NIH HHS R01 MH050047NIMH NIH HHS T32 MH019908
6 · The paper itself

Abstract

There is increasing evidence that Turner syndrome is associated with a distinct pattern of cognitive and neurophysiological characteristics. Typically this has been characterized by relative strengths in verbal skills, contrasting with relative weaknesses in arithmetic, visuospatial and executive function domains. Potential differences in social cognitive processing have also been identified. More recently, applications of neuroimaging techniques have further elucidated underlying differences in brain structure, function and connectivity in individuals with Turner syndrome. Ongoing research in this area is focused on establishing a unified mechanistic model incorporating genetic influences from the X chromosome, sex hormone contributions, neuroanatomical variation and differences in cognitive processes. This review broadly covers current understanding of how X-monosomy impacts neurocognitive phenotype both from the perspective of cognitive-behavioral and neuroimaging studies. Furthermore, relevant clinical aspects of identifying potential learning difficulties and providing anticipatory guidance for affected individuals with TS, are briefly discussed.

Indexed as

BehaviorCognitionBrainCognition DisordersExecutive FunctionFemaleHumansLearning DisabilitiesNeuroimagingNeuropsychological TestsTurner Syndrome

Identifiers

PMID22946281
PMCPMC4285374
OpenAlexW83730475

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.