ArticleDigestive diseases and sciences2013
Temperature can influence gastric accommodation and sensitivity in functional dyspepsia with epigastric pain syndrome.
Article in Digestive diseases and sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
- Beyond Medication: Integrative and Nutrition Therapies for Disorders of Gut-Brain Interaction.Gastroenterology & hepatology · 2026Article
- Development and validation of an interpretable machine learning model for non-invasive screening of precancerous gastric lesions using symptom and lifestyle data: a multicentre cohort study.EClinicalMedicine · 2026Article
- Trends and seasonal variation in the incidence and prevalence of irritable bowel syndrome in Korea: a multicenter OMOP CDM study.Frontiers in public health · 2026Article
- Application of response surface methodology (RSM) for optimization of the supercritical COFood chemistry: X · 2022Article
- Risk factors associated with functional dyspepsia in Chinese children: a cross-sectional study.BMC gastroenterology · 2021Article
- Effects of Endovascular Stent-Assisted Effects of Various Frequencies of Abdominal Naprapathy on Changes in Gastrointestinal Mucosal Cells in Spleen-Deficient Rabbits.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Robotic Setup Promises Consistent Effects of Multilocular Gastrointestinal Electrical Stimulation: First Results of a Porcine Study.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes · 2020Article
- The Role of Diet in Functional Dyspepsia Management.Frontiers in psychiatry · 2020Review
- Vagal Transient Receptor Potential Ankyrin 1 Mediates Stress-exacerbated Visceral Mechanonociception After Antral Cold Exposure.Journal of neurogastroenterology and motility · 2019Article
- Regional Brain Activity During Rest and Gastric Water Load in Subtypes of Functional Dyspepsia: A Preliminary Brain Functional Magnetic Resonance Imaging Study.Journal of neurogastroenterology and motility · 2018Article
- A Study on the Diagnostic Elements of Cold-Heat Pattern Identification by Korean Medicine Doctors: Association with Objective and Subjective Body Temperature.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- "Too hot" or "too cold": effects of meal temperature on gastric function.Digestive diseases and sciences · 2013Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundFunctional dyspepsia-epigastric pain syndrome (FD-EPS) is characterized pathophysiologically by visceral hypersensitivity, but the effect of the temperature stimulation on gastric function has been seldom studied.
aimThe purpose of this study was to investigate the effects of liquid nutrients at different temperatures on the gastric accommodation, sensitivity, and gastric-wall compliance of healthy subjects (HS) and FD-EPS patients.
methodsTen FD-EPS patients (Roma III criteria) and ten HS were recruited into the study. Intragastric pressure (IGP) and gastric perfusion were measured and compared following the administration of liquid nutrients at 37 °C on day 1 and at 8 °C on day 2.
resultsSeven patients developed abdominal discomfort or abdominal pain after being given cold liquid nutrient. The administration of liquid nutrient at 8 °C resulted in an increase of IGP in HS (P=0.044), a significant decrease in gastric perfusion (P<0.0001), a marked increase in IGP (P=0.015), and a dramatic reduction in gastric wall compliance (P=0.012) in patients compared to the effects of liquid nutrient at 37 °C. In addition, IGP in patients was lower than that in HS at 37 °C liquid nutrient (P=0.036), and the gastric perfusion volume in patients at maximal satiety was also significantly reduced at 8 °C liquid nutrient compared with HS (P=0.017).
conclusionsCold stimulation can increase the IGP in HS and FD-EPS patients, elevate the visceral sensitivity and reduce the gastric volume of FD-EPS patients. FD-EPS patients who are sensitive to cold may develop epigastric discomfort or pain.
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