Evidence map›Paper›PMID 22945410›Full record

ArticlePediatrics2012

Congenital fibrosarcoma and history of prenatal exposure to petroleum derivatives.

Juan A Ortega-García, Offie P Soldin, Fernando A López-Hernández, Leonardo Trasande, Josep Ferrís-Tortajada

Abstract readCase Reports
In one paragraph

Article in Pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Juan A Ortega-GarcíaPediatric Environmental Health Specialty Unit, Department of Pediatrics, University Hospital Virgen of Arrixaca, Murcia, Spain. ortega@pehsu.org
Offie P Soldin
Fernando A López-Hernández
Leonardo Trasande
Josep Ferrís-Tortajada
Georgetown University Medical Center · USHospital Universitario Virgen de la Arrixaca · ESLeitat Technological Center · ESNew York University · USUniversidad Politécnica de Cartagena · ES

Funding

International Exchange Program for Minority StudentsT37MD001452 · NIMHD · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI CLAUDIO, LUZ · 2005 to 2023
$4.9M
Hyopthyroidism Treatment in Aging and Thyroid CancerR01AG033867 · NIA · GEORGETOWN UNIVERSITY · PI BURMAN, KENNETH D, JONKLAAS, JACQUELINE · 2010 to 2014
$1.8M
NIA NIH HHS R01 AG033867NIMHD NIH HHS MD001452NIMHD NIH HHS T37 MD001452
6 · The paper itself

Abstract

Congenital fibrosarcoma (CFS) is a rare fibrous tissue malignancy that usually presents in the first few years of life. It is unique among human sarcomas in that it has an excellent prognosis. We describe a temporal clustering of a number of cases of CFS and investigate the possible associated prenatal risk factors. The Pediatric Environmental History, a questionnaire developed in our clinic that is instrumental in determining environmental risk factors for tumor-related disease, was essential in documenting the presence or absence of risk factors considered as human carcinogens. We found a history of exposure to petroleum products in four cases of CFS that occurred at a greater than expected rate in a short time frame-an apparent cancer cluster. We call attention to the possibility that exposure to petroleum products raises the risk of developing CFS. While future studies should focus on systematic investigation of CFS and its underlying mechanisms, this report suggests the need for proactive measures to avoid exposure to solvents and petroleum products during pregnancy.

Indexed as

ThighCarcinogens, EnvironmentalFemaleFibrosarcomaHumansInfant, NewbornMaleMaternal ExposurePaternal ExposurePetroleumRetroperitoneal NeoplasmsSoft Tissue NeoplasmsSpainSurveys and QuestionnairesCarcinogens, EnvironmentalPetroleum

Identifiers

PMID22945410
PMCPMC3457614
OpenAlexW2156687546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.