ArticleNature cell biology2012
Bending membranes.
Article in Nature cell biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 82 citations in OpenAlex.
- Effects of Macromolecular Crowding on the Structure and Dynamics of Biological Membranes.Sub-cellular biochemistry · 2025Review
- Softening in Two-Component Lipid Mixtures by Spontaneous Curvature Variance.The journal of physical chemistry. B · 2024Article
- A tripartite organelle platform links growth factor receptor signaling to mitochondrial metabolism.Nature communications · 2024Article
- MEDUSA: A cloud-based tool for the analysis of X-ray diffuse scattering to obtain the bending modulus from oriented membrane stacks.PLoS computational biology · 2024Article
- Softening in two-component lipid mixtures by spontaneous curvature variance.bioRxiv : the preprint server for biology · 2023Article
- Crowding-induced membrane remodeling: Interplay of membrane tension, polymer density, architecture.Biophysical journal · 2022Article
- Molecular mechanisms of steric pressure generation and membrane remodeling by disordered proteins.Biophysical journal · 2022Article
- Article
- Exposure ofNutrients · 2021Article
- Dynamic interplay between cell membrane tension and clathrin-mediated endocytosis.Biology of the cell · 2021Review
- Nanodissected elastically loaded clathrin lattices relax to increased curvature.Science advances · 2021Article
- Characterisation of a synthetic Archeal membrane reveals a possible new adaptation route to extreme conditions.Communications biology · 2021Article
- Spatial extent of a single lipid's influence on bilayer mechanics.Physical review. E · 2021Article
- Mechanisms of negative membrane curvature sensing and generation by ESCRT III subunit Snf7.Protein science : a publication of the Protein Society · 2020Article
- Modifying Membrane Morphology and Interactions with DNA Origami Clathrin-Mimic Networks.ACS nano · 2019Article
- Kinetics of Histidine-Tagged Protein Association to Nickel-Decorated Liposome Surfaces.Langmuir : the ACS journal of surfaces and colloids · 2019Article
- Modeling Membrane Curvature Generation due to Membrane⁻Protein Interactions.Biomolecules · 2018Review
- Ectopic Neo-Formed Intracellular Membranes inBiomolecules · 2018Review
- The role of traction in membrane curvature generation.Molecular biology of the cell · 2018Article
- Receptor-mediated endocytosis generates nanomechanical force reflective of ligand identity and cellular property.Journal of cellular physiology · 2018Article
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Abstract
It is widely assumed that peripheral membrane proteins induce intracellular membrane curvature by the asymmetric insertion of a protein segment into the lipid bilayer, or by imposing shape by adhesion of a curved protein domain to the membrane surface. Two papers now provide convincing evidence challenging these views. The first shows that specific assembly of a clathrin protein scaffold, coupled to the membrane, seems to be the most prevalent mechanism for bending a lipid bilayer in a cell. The second reports that membrane crowding, driven by protein-protein interactions, can also drive membrane bending, even in the absence of any protein insertion into the bilayer.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.