ArticleMolecular and cellular biology1990
A murine fer testis-specific transcript (ferT) encodes a truncated Fer protein.
Article in Molecular and cellular biology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 86 citations in OpenAlex.
- Fer and FerT: A New Regulatory Link between Sperm and Cancer Cells.International journal of molecular sciences · 2023Review
- Article
- Sponges: A Reservoir of Genes Implicated in Human Cancer.Marine drugs · 2018Review
- Article
- The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm.Development (Cambridge, England) · 2016Article
- Intronic promoter drives the BORIS-regulated expression of FerT in colon carcinoma cells.The Journal of biological chemistry · 2012Article
- Downregulation of Fer induces PP1 activation and cell-cycle arrest in malignant cells.Oncogene · 2006Article
- Gamma interferon down-regulates Fer and induces its association with inactive Stat3 in colon carcinoma cells.Oncogene · 2002Article
- Mice devoid of fer protein-tyrosine kinase activity are viable and fertile but display reduced cortactin phosphorylation.Molecular and cellular biology · 2001Article
- Targeted disruption of the murine fps/fes proto-oncogene reveals that Fps/Fes kinase activity is dispensable for hematopoiesis.Molecular and cellular biology · 1999Article
- Involvement of the tyrosine kinase fer in cell adhesion.Molecular and cellular biology · 1998Article
- Fert is on mouse chromosome 11, not chromosome 17.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Meiosis-dependent tyrosine phosphorylation of a yeast protein related to the mouse p51ferT.Molecular & general genetics : MGG · 1994Article
- Testis-specific mak protein kinase is expressed specifically in the meiotic phase in spermatogenesis and is associated with a 210-kilodalton cellular phosphoprotein.Molecular and cellular biology · 1993Article
- mdm2 expression is induced by wild type p53 activity.The EMBO journal · 1993Article
- Molecular cloning, nucleotide sequence and expression of a cDNA encoding an intracellular protein tyrosine phosphatase, PTPase-2, from mouse testis and T-cells.Molecular and cellular biochemistry · 1992Article
- Characterization of the testes-specific pim-1 transcript in rat.Nucleic acids research · 1992Article
- An analysis of vertebrate mRNA sequences: intimations of translational control.The Journal of cell biology · 1991Review
- Methylation patterns of testis-specific genes.Proceedings of the National Academy of Sciences of the United States of America · 1991Article
- Nuclear and cytoplasmic location of the FER tyrosine kinase.Molecular and cellular biology · 1991Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A cDNA for a potential tyrosine kinase-encoding mRNA was isolated from a mouse testis cDNA library. In a survey of eight mouse tissues, a transcript of 2.4 kilobases restricted to testis tissue was found. The mRNA encodes a 453-amino-acid protein of 51,383 daltons, the smallest tyrosine kinase protein ever described. RNA synthesized from the cDNA template directs the synthesis of a 51,000-Mr protein in a cell-free translation system. The carboxy-terminal 409 amino acids are 98 and 90% identical to the carboxy halves of the rat and human Fer proteins, respectively. This suggests that the cDNA represents an alternatively spliced testis-specific fer mRNA and is therefore termed by us ferT. On the basis of the appearance time of the fer mRNA in the testis of maturing neonatal mice, we speculate on the role played by this protein in the development of this organ.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.