Evidence map›Paper›PMID 22943579›Full record

ReviewBritish journal of clinical pharmacology2013

Applied clinical pharmacology and public health in rural Asia--preventing deaths from organophosphorus pesticide and yellow oleander poisoning.

Michael Eddleston

Open access · bronzeAbstract readReview
In one paragraph

Review in British journal of clinical pharmacology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. The role of alcohol use in pesticide suicide and self-harm: a scoping review.Social psychiatry and psychiatric epidemiology · 2024
    Article
  3. Article
  4. Review
  5. Deliberate Self-poisoning due to Plant Toxins: Verdant Footprints of the Past into the Present.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2021
    Article
  6. Pesticide-Poisoned Patients: Can They Be Used as Potential Organ Donors?Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2018
    Review
  7. Toxicology in the Service of Patient and Medication Safety: a Selected Glance at Past and Present Innovations.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2015
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 3 countries.

Michael EddlestonClinical Pharmacology Unit, University/BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK. m.eddleston@ed.ac.uk
University of Edinburgh · GB

Funding

Chief Scientist Office SCD/05Wellcome Trust 063560Wellcome Trust 085979Wellcome Trust 090886Wellcome Trust 090958
6 · The paper itself

Abstract

Self-poisoning with pesticides or plants is a major clinical problem in rural Asia, killing several hundred thousand people every year. Over the last 17 years, our clinical toxicology and pharmacology group has carried out clinical studies in the North Central Province of Sri Lanka to improve treatment and reduce deaths. Studies have looked at the effectiveness of anti-digoxin Fab in cardiac glycoside plant poisoning, multiple dose activated charcoal in all poisoning, and pralidoxime in moderate toxicity organophosphorus insecticide poisoning. More recently, using a Haddon matrix as a guide, we have started conducting public health and animal studies to find strategies that may work outside of the hospital. Based on the 2009 GSK Research in Clinical Pharmacology prize lecture, this review shows the evolution of the group's research from a clinical pharmacology approach to one that studies possible interventions at multiple levels, including the patient, the community and government legislation.

Indexed as

AcetylcholineAntidotesAsiaBiomedical ResearchCharcoalCholinergic AgonistsHumansNeriumOrganophosphate PoisoningPesticidesPharmacology, ClinicalPralidoxime CompoundsRandomized Controlled Trials as TopicRural HealthSri LankaAcetylcholineAntidotesCharcoalCholinergic AgonistsPesticidespralidoximePralidoxime Compounds

Identifiers

PMID22943579
PMCPMC3635588
OpenAlexW1887606779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.