ArticleVirology journal2012
A sensitive and specific blocking ELISA for the detection of rabbit calicivirus RCV-A1 antibodies.
Article in Virology journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization.Scientific reports · 2024Article
- First Detection of Benign Rabbit Caliciviruses in Chile.Viruses · 2024Article
- Optimising the Delivery of RHDV to Rabbits for Biocontrol: An Experimental Evaluation of Two Novel Methods of Virus Delivery.Viruses · 2023Article
- Article
- Passive Immunisation against RHDV2 Induces Protection against Disease but Not Infection.Vaccines · 2021Article
- A Review on the Methods Used for the Detection and Diagnosis of Rabbit Hemorrhagic Disease Virus (RHDV).Microorganisms · 2021Review
- High-throughput Luminex xMAP assay for simultaneous detection of antibodies against rabbit hemorrhagic disease virus, Sendai virus and rabbit rotavirus.Archives of virology · 2019Article
- Elucidation of the pathology and tissue distribution of Lagovirus europaeus GI.2/RHDV2 (rabbit haemorrhagic disease virus 2) in young and adult rabbits (Oryctolagus cuniculus).Veterinary research · 2018Article
- Rapid detection of three rabbit pathogens by use of the Luminex x-TAG assay.BMC veterinary research · 2018Article
- Detection and Circulation of a Novel Rabbit Hemorrhagic Disease Virus in Australia.Emerging infectious diseases · 2018Article
- Benign Rabbit Calicivirus in New Zealand.Applied and environmental microbiology · 2017Article
- An in vivo system for directed experimental evolution of rabbit haemorrhagic disease virus.PloS one · 2017Article
- Article
- Distribution and prevalence of the Australian non-pathogenic rabbit calicivirus is correlated with rainfall and temperature.PloS one · 2014Article
- The non-pathogenic Australian rabbit calicivirus RCV-A1 provides temporal and partial cross protection to lethal Rabbit Haemorrhagic Disease Virus infection which is not dependent on antibody titres.Veterinary research · 2013Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntibodies to non-pathogenic rabbit caliciviruses (RCVs) cross-react in serological tests for rabbit hemorrhagic disease virus (RHDV) and vice versa, making epidemiological studies very difficult where both viruses occur. It is important to understand the distribution and interaction of the two viruses because the highly pathogenic RHDV has been used as a biocontrol agent for wild rabbits in Australia and New Zealand for the past 17 years. The presence of the benign RCV Australia 1 (RCV-A1) is considered a key factor for the failure of RHDV mediated rabbit control in cooler, wetter areas of Australia.
resultsA highly sensitive and specific blocking ELISA was developed for the detection of RCV-A1 antibodies. When sera from rabbits with a known infection history for either RCV-A1 or RHDV were tested, this assay showed 100% sensitivity and no cross-reactivity with RHDV sera (100% specificity).
conclusionsThis new ELISA not only allows the detection of RCV-A1 at a population level, but also permits the serological status of individual rabbits to be determined more reliably than previously described methods. This robust and simple to perform assay is therefore the tool of choice for studying RCV-A1 epidemiology in Australian wild rabbit populations.
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