ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2012
Underutilization of aspirin for primary prevention of cardiovascular disease among HIV-infected patients.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical practice guideline for the management of chronic kidney disease in patients infected with HIV: 2014 update by the HIV Medicine Association of the Infectious Diseases Society of America.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014Guideline
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- Correlates of physical activity among people living with and without HIV in rural Uganda.Frontiers in reproductive health · 2023Article
- Novel Role of the SIRT1 in Endocrine and Metabolic Diseases.International journal of biological sciences · 2023Review
- Pattern of arterial inflammation and inflammatory markers in people living with HIV compared with uninfected people.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Multimorbidity Burden and Incident Heart Failure Among People With and Without HIV: The HIV-HEART Study.Mayo Clinic proceedings. Innovations, quality & outcomes · 2022Article
- Perspectives of HIV specialists and cardiologists on the specialty referral process for people living with HIV: a qualitative descriptive study.BMC health services research · 2022Article
- Polypharmacy and frailty among persons with HIV.AIDS care · 2021Article
- Cardiovascular disease and prevention among people living with HIV in South Florida.Medicine · 2021 · on this mapObservational
- Perspectives of Chronic Disease Management Among Persons with HIV: A Qualitative Study.Patient preference and adherence · 2021Article
- Cardiovascular Disease Risk Management in Persons With HIV: Does Clinician Specialty Matter?Open forum infectious diseases · 2020Article
- HIV and cardiovascular disease.The lancet. HIV · 2020Review
- Polypharmacy in HIV: recent insights and future directions.Current opinion in HIV and AIDS · 2020Review
- Why Do People Living with HIV Adhere to Antiretroviral Therapy and Not Comorbid Cardiovascular Disease Medications? A Qualitative Inquiry.Patient preference and adherence · 2020Article
- Rationale and design of a nurse-led intervention to extend the HIV treatment cascade for cardiovascular disease prevention trial (EXTRA-CVD).American heart journal · 2019Article
- HIV and Aging: Reconsidering the Approach to Management of Comorbidities.Infectious disease clinics of North America · 2019Review
- Characteristics, Prevention, and Management of Cardiovascular Disease in People Living With HIV: A Scientific Statement From the American Heart Association.Circulation · 2019Review
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Abstract
backgroundIndividuals infected with human immunodeficiency virus (HIV) are at increased risk for cardiovascular disease (CVD) events compared with uninfected persons. However, little is known about HIV provider practices regarding aspirin (ASA) for primary prevention of CVD.
methodsA cross-sectional study was conducted among patients attending the University of Alabama at Birmingham 1917 HIV Clinic during 2010 to determine the proportion receiving ASA for primary prevention of CVD and identify factors associated with ASA prescription. Ten-year risk for CVD events was calculated for men aged 45-79 and women aged 55-79. The 2009 US Preventive Services Task Force (USPSTF) guidelines were used to determine those qualifying for primary CVD prevention.
resultsAmong 397 patients who qualified to receive ASA (mean age, 52.2 years, 94% male, 36% African American), only 66 (17%) were prescribed ASA. In multivariable logistic regression analysis, diabetes mellitus (odds ratio [OR], 2.60; 95% confidence interval [CI], 1.28-5.27), hyperlipidemia (OR, 3.42; 95% CI, 1.55-7.56), and current smoking (OR, 1.87; 95% CI, 1.03-3.41) were significantly associated with ASA prescription. Odds of ASA prescription more than doubled for each additional CVD-related comorbidity present among hypertension, diabetes, hyperlipidemia, and smoking (OR, 2.13, 95% CI, 1.51-2.99).
conclusionsIn this HIV-infected cohort, fewer than 1 in 5 patients in need received ASA for primary CVD prevention. Escalating likelihood of ASA prescription with increasing CVD-related comorbidity count suggests that providers may be influenced more by co-occurrence of these diagnoses than by USPSTF guidelines. In the absence of HIV-specific guidelines, interventions to improve HIV provider awareness of and adherence to existing general population guidelines on CVD risk reduction are needed.
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