Evidence map›Paper›PMID 22941885›Full record

ArticleEuropean respiratory review : an official journal of the European Respiratory Society2012

An integrated approach in the diagnosis of smoking-related interstitial lung diseases.

Antonella Caminati, Alberto Cavazza, Nicola Sverzellati, Sergio Harari

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in European respiratory review : an official journal of the European Respiratory Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02665546 (Evaluation of Exercise Capacity and Mechanisms of Exercise Limitation in Patients With Pulmonary Langerhans Cell Histiocytosis), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02665546 completednot on this mapstarted 2016, after this paper: background citation

Evaluation of Exercise Capacity and Mechanisms of Exercise Limitation in Patients With Pulmonary Langerhans Cell Histiocytosis

TypeobservationalSponsorInCor Heart InstituteRan2016 to 2018Enrolled35ConditionsLangerhans Cell Histiocytosis
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. TTC3 contributes to TGF-βCell death & disease · 2019
    Article
  8. Article
  9. Review
  10. Article
  11. Action plans for COPD: strategies to manage exacerbations and improve outcomes.International journal of chronic obstructive pulmonary disease · 2016
    Review
  12. Are interstitial lung abnormalities associated with COPD? A nested case-control study.International journal of chronic obstructive pulmonary disease · 2016
    Article
  13. ATS Core Curriculum 2015. Part I: Adult Pulmonary Medicine.Annals of the American Thoracic Society · 2015
    Article
  14. Smoking and interstitial lung diseases.European respiratory review : an official journal of the European Respiratory Society · 2015
    Review
  15. Article
  16. Inflammatory lung disease in Rett syndrome.Mediators of inflammation · 2014
    Article
  17. Article
  18. Article
  19. Global effort against rare and orphan diseases.European respiratory review : an official journal of the European Respiratory Society · 2012
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Antonella CaminatiU.O. Pneumologia e Terapia Semi-Intensiva Respiratoria, Servizio di Fisiopatologia Respiratoria ed Emodinamica Polmonare, Ospedale San Giuseppe - MultiMedica, Milan, Italy.
Alberto Cavazza
Nicola Sverzellati
Sergio Harari
Ospedale San Giuseppe · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cigarette smoke consists of several chemical compounds with a variety of effects in many organs. In the lung, apart being the main cause of chronic obstructive pulmonary disease, carcinoma and idiopathic spontaneous pneumothorax, tobacco smoke is associated with interstitial lung diseases (ILDs), including respiratory bronchiolitis-associated ILD (RB-ILD), desquamative interstitial pneumonia (DIP), pulmonary Langerhans' cell histiocytosis (PLCH), idiopathic pulmonary fibrosis, acute eosinophilic pneumonia, ILD in rheumatoid arthritis and pulmonary haemorrhage in Goodpasture syndrome. This review will focus on the diseases with a stronger epidemiological association with tobacco smoke, namely RB-ILD, DIP and PLCH. Although the exact pathogenetic evidence linking smoking with these disorders is still not completely understood, there is growing evidence that tobacco smoke targets the terminal or respiratory bronchioles in these diseases, and the differences are reflective of the degree of severity of small airway and parenchymal reaction to the smoke exposure. Despite considerable clinical, radiological and histological overlap between RB-ILD, DIP and PLCH, it is useful to retain the separate classifications for prognostic and therapeutic implications.

Indexed as

HumansLungLung Diseases, InterstitialPredictive Value of TestsPrognosisRadiographyRisk AssessmentRisk FactorsSmokingSmoking CessationSmoking Prevention

Identifiers

PMID22941885
PMCPMC9487338
OpenAlexW2156291394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.