Evidence map›Paper›PMID 22941732›Full record

ArticleGenetic epidemiology2012

Loss of power in two-stage residual-outcome regression analysis in genetic association studies.

Ronglin Che, Alison A Motsinger-Reif, Chad C Brown

Abstract readLetterComment
In one paragraph

Article in Genetic epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ronglin CheBioinformatics Research Center,, Department of Statistics, North Carolina State University, Raleigh, North Carolina.
Alison A Motsinger-Reif
Chad C Brown

Funding

Genetic Etiology of Cancer Drug ResponseR01CA161608 · NCI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI WILTSHIRE, TIM, WRIGHT, FRED A. · 2012 to 2021
$4.0M
Biostatistics Training in the Omics EraT32GM081057 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI MUSE, SPENCER V. · 2007 to 2019
$2.5M
Genetic Basis of Genotype-by-Environment Interactions Underlying Physiological MoR01GM098856 · NIGMS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI MOTSINGER-REIF, ALISON, REED, LAURA K · 2011 to 2015
$1.3M
NCI NIH HHS NCI R01 CA161608NCI NIH HHS R01 CA161608NIGMS NIH HHS R01 GM098856NIGMS NIH HHS T32 GM081057NIGMS NIH HHS T32GM081057
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiasGenetic Association StudiesRegression AnalysisFemaleHumansMaledegrees of freedomloss of powertwo-stage regression

Identifiers

PMID22941732
PMCPMC4350584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.