ReviewSeminars in immunopathology2012
Microbial regulation of allergic responses to food.
Review in Seminars in immunopathology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 48 citations in OpenAlex.
- Lactobacillus rhamnosus GG-supplemented formula expands butyrate-producing bacterial strains in food allergic infants.The ISME journal · 2016Trial
- Amelioration Effect ofFoods (Basel, Switzerland) · 2024Article
- Acceptive Immunity: The Role of Fucosylated Glycans in Human Host-Microbiome Interactions.International journal of molecular sciences · 2021Review
- Alteration of Intestinal Microbiota Composition in Oral Sensitized C3H/HeJ Mice Is Associated With Changes in Dendritic Cells and T Cells in Mesenteric Lymph Nodes.Frontiers in immunology · 2021Article
- Garlic lowers blood pressure in hypertensive subjects, improves arterial stiffness and gut microbiota: A review and meta-analysis.Experimental and therapeutic medicine · 2020Article
- Immune Activation in Functional Gastrointestinal Disorders.Gastroenterology & hepatology · 2019Article
- Milk and Meat Allergens fromNutrients · 2019Article
- The Microbiome and Food Allergy.Annual review of immunology · 2019Review
- The impact of modifiable risk factor reduction on childhood asthma development.Clinical and translational medicine · 2018Review
- The Effect of Kyolic Aged Garlic Extract on Gut Microbiota, Inflammation, and Cardiovascular Markers in Hypertensives: The GarGIC Trial.Frontiers in nutrition · 2018Article
- Perinatal antibiotic exposure alters composition of murine gut microbiota and may influence later responses to peanut antigen.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2018Article
- The Potential for Emerging Microbiome-Mediated Therapeutics in Asthma.Current allergy and asthma reports · 2017Review
- The Influence of the Microbiome on Allergic Sensitization to Food.Journal of immunology (Baltimore, Md. : 1950) · 2017Review
- Multifactorial Modulation of Food-Induced Anaphylaxis.Frontiers in immunology · 2017Review
- Meat Intake and the Dose of Vitamin BInternational journal of tryptophan research : IJTR · 2017Review
- Regulatory T cells in allergic diseases.The Journal of allergy and clinical immunology · 2016Review
- Food, health, and complexity: towards a conceptual understanding to guide collaborative public health action.BMC public health · 2016Article
- Review
- New developments providing mechanistic insight into the impact of the microbiota on allergic disease.Clinical immunology (Orlando, Fla.) · 2015Review
- The role of the commensal microbiota in the regulation of tolerance to dietary allergens.Current opinion in allergy and clinical immunology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The incidence of food allergy in developed countries is rising at a rate that cannot be attributed to genetic variation alone. In this review, we discuss the environmental factors that may contribute to the increasing prevalence of potentially fatal anaphylactic responses to food. Decreased exposure to enteric infections due to advances in vaccination and sanitation, along with the adoption of high-fat (Western) diets, antibiotic use, Cesarean birth, and formula feeding of infants, have all been implicated in altering the enteric microbiome away from its ancestral state. This collection of resident commensal microbes performs many important physiological functions and plays a central role in the development of the immune system. We hypothesize that alterations in the microbiome interfere with immune system maturation, resulting in impairment of IgA production, reduced abundance of regulatory T cells, and Th2-skewing of baseline immune responses which drive aberrant responses to innocuous (food) antigens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.