Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2013
Somatic symptoms in cancer patients trajectory over 12 months and impact on functional status and disability.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03905876 (Psychological Experience of the End of the Treatment During a Clincal Trial of the Early Phase and Role of the Initial prédispositions), which is not on this map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Psychological Experience of the End of the Treatment During a Clincal Trial of the Early Phase and Role of the Initial prédispositions ( VRAIMENT)
Who cites it
25 citing papers in PubMed, 41 citations in OpenAlex.
- Patient Engagement With an Automated Telephone Symptom Management Intervention: Predictors and Outcomes.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2020Trial
- The Role of Inflammation in the Pain, Fatigue, and Sleep Disturbance Symptom Cluster in Advanced Cancer.Journal of pain and symptom management · 2018Trial
- Randomized controlled pilot study of mindfulness-based stress reduction for persistently fatigued cancer survivors.Psycho-oncology · 2015Trial
- Cost effectiveness of telecare management for pain and depression in patients with cancer: results from a randomized trial.General hospital psychiatryTrial
- Identifying the trajectory of SPPADE symptoms in patients with cancer using electronic health record data.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Time to consider the potential role of alternative resistance training methods in cancer management?Journal of sport and health science · 2023Review
- Pain or fatigue: which correlates more with suffering in hospitalized cancer patients?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021Article
- The positive effect of social support on psychological distress among Chinese lung cancer patients: The mediating role of self-esteem.Nursing open · 2021Article
- The Past, Present, and Future of American Cancer Rehabilitation.Physical therapy research · 2021Review
- Yoga for symptom management in oncology: A review of the evidence base and future directions for research.Cancer · 2019Review
- Association Between Symptom Burden and Physical Function in Older Patients with Cancer.Journal of the American Geriatrics Society · 2019Article
- Risk of malnutrition and emotional distress as factors affecting health-related quality of life in patients with resected cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019Observational
- Pretreatment Psychoneurological Symptoms and Their Association With Longitudinal Cognitive Function and Quality of Life in Older Breast Cancer Survivors.Journal of pain and symptom management · 2019Article
- Characteristics Associated With Physical Function Trajectories in Older Adults With Cancer During Chemotherapy.Journal of pain and symptom management · 2018Article
- Relationship among symptom clusters, quality of life, and treatment-specific optimism in patients with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Article
- Article
- Cancer-related loneliness mediates the relationships between social constraints and symptoms among cancer patients.Journal of behavioral medicine · 2018Article
- Effects of web-based interventions on cancer patients' symptoms: review of randomized trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018Review
- A Guide to Inpatient Cancer Rehabilitation: Focusing on Patient Selection and Evidence-Based Outcomes.PM & R : the journal of injury, function, and rehabilitation · 2017Review
- Who experiences higher and increasing breathlessness in advanced cancer? The longitudinal EPCCS Study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
purposeCross-sectional studies have established the prevalence and functional impairment of somatic symptoms in cancer patients. The purpose of this study was to determine the trajectory and adverse consequences of such symptoms over time.
methodsSecondary analysis of longitudinal data from 405 cancer patients enrolled in a telecare management trial for pain and/or depression. Somatic symptom burden was measured with a 22-item scale at baseline, 1, 3, 6, and 12 months. Outcomes included the SF-12 Physical Component Summary (PCS) and Mental Component Summary (MCS) scores, the Sheehan Disability Scale (SDS) score, and self-reported total disability days. Mixed methods repeated measures analyses were conducted to determine whether antecedent change in somatic symptom burden predicted functional status and disability.
resultsSymptoms were highly prevalent at baseline, with 15 of the 22 symptoms endorsed by more than half of the patients. A rather constant cross-sectional prevalence over 12 months at the group level belied a quite different trajectory at the patient level where the median persistence, resolution, and incidence rates for 14 of the most common symptoms were 39%, 37%, and 24%, respectively. A clinically significant (i.e., five points) reduction in somatic symptom burden predicted improvement in PCS, MCS, and SDS (all P < 0.001), as well as a lower likelihood of ≥14 disability days in the past 4 weeks (odds ratio, 0.84; 95% CI, 0.74 to 0.95).
conclusionsSomatic symptoms remain burdensome in cancer patients over 12 months and symptom improvement predicts significantly better functional status and less disability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.