ArticleInternational journal of legal medicine2012
Haplogrouping mitochondrial DNA sequences in Legal Medicine/Forensic Genetics.
Article in International journal of legal medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Quantitation of human mitochondrial DNA and whole mtGenomes sequencing of fingernail/hair shaft samples.Forensic sciences research · 2025Article
- Kaspar Hauser's alleged noble origin - New molecular genetic analyses resolve the controversy.iScience · 2024Article
- Analysis of maternal genetic structure of mitochondrial DNA control region from Tai-Kadai-speaking Buyei population in southwestern China.BMC genomics · 2024Article
- Deciphering the maternal ancestral lineage of Greek Cypriots, Armenian Cypriots and Maronite Cypriots.PloS one · 2024Article
- HaploCart: Human mtDNA haplogroup classification using a pangenomic reference graph.PLoS computational biology · 2023Article
- Mitochondrial Haplogroup Classification of Ancient DNA Samples Using Haplotracker.BioMed research international · 2022Article
- Fine-Tuning Phylogenetic Alignment and Haplogrouping of mtDNA Sequences.International journal of molecular sciences · 2021Article
- Developmental validation of the MGIEasy Signature Identification Library Prep Kit, an all-in-one multiplex system for forensic applications.International journal of legal medicine · 2021Article
- A single nucleotide polymorphism panel for individual identification and ancestry assignment in Caucasians and four East and Southeast Asian populations using a machine learning classifier.Forensic science, medicine, and pathology · 2019Article
- MtDNA As a Cancer Marker: A Finally Closed Chapter?Current genomics · 2017Review
- HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing.Nucleic acids research · 2016Article
- Article
- Phy-Mer: a novel alignment-free and reference-independent mitochondrial haplogroup classifier.Bioinformatics (Oxford, England) · 2015Article
- Genomic insights on the ethno-history of the Maya and the 'Ladinos' from Guatemala.BMC genomics · 2015Article
- Article
- Mitogenomes from The 1000 Genome Project reveal new Near Eastern features in present-day Tuscans.PloS one · 2015Article
- Cuba: exploring the history of admixture and the genetic basis of pigmentation using autosomal and uniparental markers.PLoS genetics · 2014Article
- Haplotype diversity in mitochondrial DNA hypervariable region in a population of southeastern Brazil.International journal of legal medicine · 2014Article
- The case for the continuing use of the revised Cambridge Reference Sequence (rCRS) and the standardization of notation in human mitochondrial DNA studies.Journal of human genetics · 2014Review
- Mitochondrial DNA variants in obesity.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Haplogrouping refers to the classification of (partial) mitochondrial DNA (mtDNA) sequences into haplogroups using the current knowledge of the worldwide mtDNA phylogeny. Haplogroup assignment of mtDNA control-region sequences assists in the focused comparison with closely related complete mtDNA sequences and thus serves two main goals in forensic genetics: first is the a posteriori quality analysis of sequencing results and second is the prediction of relevant coding-region sites for confirmation or further refinement of haplogroup status. The latter may be important in forensic casework where discrimination power needs to be as high as possible. However, most articles published in forensic genetics perform haplogrouping only in a rudimentary or incorrect way. The present study features PhyloTree as the key tool for assigning control-region sequences to haplogroups and elaborates on additional Web-based searches for finding near-matches with complete mtDNA genomes in the databases. In contrast, none of the automated haplogrouping tools available can yet compete with manual haplogrouping using PhyloTree plus additional Web-based searches, especially when confronted with artificial recombinants still present in forensic mtDNA datasets. We review and classify the various attempts at haplogrouping by using a multiplex approach or relying on automated haplogrouping. Furthermore, we re-examine a few articles in forensic journals providing mtDNA population data where appropriate haplogrouping following PhyloTree immediately highlights several kinds of sequence errors.
Indexed as
Identifiers
22940763What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.