Evidence map›Paper›PMID 22940744›Full record

ReviewEuropean archives of psychiatry and clinical neuroscience2012

Multimodal functional and structural imaging investigations in psychosis research.

C Christoph Schultz, Paolo Fusar-Poli, Gerd Wagner, Kathrin Koch, Claudia Schachtzabel, Oliver Gruber, Heinrich Sauer, Ralf G M Schlösser

Abstract readReview
PubMed Publisher
In one paragraph

Review in European archives of psychiatry and clinical neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Bridging Gaps in Sundown Syndrome Research: a Scoping Review and Roadmap for Future Multimodal Approaches.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. FDG-PET scans in patients with Kraepelinian and non-Kraepelinian schizophrenia.European archives of psychiatry and clinical neuroscience · 2016
    Article
  15. Multimodal fusion of brain imaging data: A key to finding the missing link(s) in complex mental illness.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2016
    Article
  16. Review
  17. Article
  18. Review
  19. Current status and future role of brain PET/MRI in clinical and research settings.European journal of nuclear medicine and molecular imaging · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

C Christoph SchultzDepartment of Psychiatry and Psychotherapy, Jena University Hospital, Philosophenweg 3, 07740 Jena, Germany. christoph.schultz@med.uni-jena.de
Paolo Fusar-Poli
Gerd Wagner
Kathrin Koch
Claudia Schachtzabel
Oliver Gruber
Heinrich Sauer
Ralf G M Schlösser

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Substantial pathophysiological questions about the relationship of brain pathologies in psychosis can only be answered by multimodal neuroimaging approaches combining different imaging modalities such as structural MRI (sMRI), functional MRI (fMRI), diffusion tensor imaging (DTI), positron emission tomography (PET) and magnetic-resonance spectroscopy. In particular, the multimodal imaging approach has the potential to shed light on the neuronal mechanisms underlying the major brain structural and functional pathophysiological features of schizophrenia and high-risk states such as prefronto-temporal gray matter reduction, altered higher-order cognitive processing, or disturbed dopaminergic and glutamatergic neurotransmission. In recent years, valuable new findings have been revealed in these fields by multimodal imaging studies mostly reflecting a direct and aligned correlation of brain pathologies in psychosis. However, the amount of multimodal studies is still limited, and further efforts have to be made to consolidate previous findings and to extend the scope to other pathophysiological parameters contributing to the pathogenesis of psychosis. Here, investigating the genetic foundations of brain pathology relationships is a major challenge for future multimodal imaging applications in psychosis research.

Indexed as

Biomedical ResearchBrainPsychotic DisordersBrain MappingCognition DisordersHumansImaging, Three-DimensionalMeta-Analysis as TopicNeuroimagingRadionuclide Imaging

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.