Trial reportThe Journal of thoracic and cardiovascular surgery2013
Superior cavopulmonary anastomosis timing and outcomes in infants with single ventricle.
Trial report in The Journal of thoracic and cardiovascular surgery, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- Variation in care for infants undergoing the Stage II palliation for hypoplastic left heart syndrome.Cardiology in the young · 2018Trial
- Trial
- Achieving an Optimal Outcome After Stage 1 Palliation for Hypoplastic Left Heart Syndrome and Variants: Frequency, Associated Factors, and Subsequent Outcomes.Journal of the American Heart Association · 2024Article
- The Second Interstage Period Is Just as "Risky" as the First in HLHS.JACC. Advances · 2024Article
- Autologous Cardiac Stem Cell Injection in Patients with Hypoplastic Left Heart Syndrome (CHILD Study).Pediatric cardiology · 2022Article
- Factors influencing length of intensive care unit stay following a bidirectional cavopulmonary shunt.Interactive cardiovascular and thoracic surgery · 2021Article
- Surgical Timing and Outcomes of Unilateral Versus Bilateral Superior Cavopulmonary Anastomosis: An Analysis of Pediatric Heart Network Public Databases.Pediatric cardiology · 2021Article
- Loss of Ventricular Function After Bidirectional Cavopulmonary Connection: Who Is at Risk?Pediatric cardiology · 2020Article
- Decreasing Interstage Mortality After the Norwood Procedure: A 30-Year Experience.Journal of the American Heart Association · 2020Article
- Center Variability in Timing of Stage 2 Palliation and Association with Interstage Mortality: A Report from the National Pediatric Cardiology Quality Improvement Collaborative.Pediatric cardiology · 2016Article
- Effects of race, ethnicity, and gender on surgical mortality in hypoplastic left heart syndrome.Pediatric cardiology · 2013Article
- The Outcomes of Superior Cavopulmonary Connection Operation: a Single Center Experience.Brazilian journal of cardiovascular surgeryArticle
Corrections and comments
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Authors and funding
14 authors at 12 institutions in 3 countries.
Funding
Abstract
objectivesWe sought to identify factors associated with the timing and surgical outcomes of the superior cavopulmonary anastomosis.
methodsThe Pediatric Heart Network's Infant Single Ventricle trial database identified participants who underwent superior cavopulmonary anastomosis. Factors potentially associated with age at superior cavopulmonary anastomosis, length of stay and death by 14 months of age were evaluated. Factors included subject demographics, cardiac anatomy, measures from neonatal hospitalization and pre-superior cavopulmonary anastomosis visit, adverse events, echocardiographic variables, intraoperative variables, superior cavopulmonary anastomosis type, and number of concurrent cardiac surgical procedures. Age at superior cavopulmonary anastomosis was analyzed using Cox proportional hazards regression. Natural log length of stay was analyzed by multiple linear regression.
resultsSuperior cavopulmonary anastomosis was performed in 193 subjects at 5.2 months of age (interquartile range, 4.2, 6.2) and weight of 5.9 kg (interquartile range, 5.3, 6.6). The median length of stay was 7 days (interquartile range, 6, 10). There were 3 deaths and 1 transplant during the superior cavopulmonary anastomosis hospitalization, and 3 deaths and 3 transplants between discharge and 14 months of age. Age at superior cavopulmonary anastomosis was associated with center and interstage adverse events. A longer length of stay was associated with younger age and greater case complexity. Superior cavopulmonary anastomosis type, valve regurgitation, ventricular ejection fraction, and ventricular end-diastolic pressure were not independently associated with age at superior cavopulmonary anastomosis or the length of stay.
conclusionsGreater case complexity and more frequent interstage adverse events are associated with an earlier age at superior cavopulmonary anastomosis. Significant variation in age at superior cavopulmonary anastomosis among centers, independent of subject factors, highlights a lack of consensus regarding the optimal timing. Factors associated with length of stay could offer insights for improving presuperior cavopulmonary anastomosis care and surgical outcome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.