ArticleTrends in endocrinology and metabolism: TEM2012
Metabolic master regulators: sharing information among multiple systems.
Article in Trends in endocrinology and metabolism: TEM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed.
- Food Coloring Additives and Incidence of Type 2 Diabetes in the NutriNet-Santé Prospective Cohort.Diabetes care · 2026Article
- Reactive oxygen species: role in obesity and mitochondrial energy efficiency.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Cysteine residues in signal transduction and its relevance in pancreatic beta cells.Frontiers in endocrinology · 2023Review
- Cholecystectomy as a risk factor for metabolic dysfunction-associated fatty liver disease: unveiling the metabolic and chronobiologic clues behind the bile acid enterohepatic circulation.Journal of physiology and biochemistry · 2021Review
- Redox Homeostasis in Pancreatic β-Cells: From Development to Failure.Antioxidants (Basel, Switzerland) · 2021Review
- Assessing Different Temporal Scales of Calcium Dynamics in Networks of Beta Cell Populations.Frontiers in physiology · 2021Article
- Crocetin Isolated from the Natural Food Colorant Saffron Reduces Intracellular Fat in 3T3-L1 Adipocytes.Foods (Basel, Switzerland) · 2020Article
- Exercise-induced α-ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1-dependent adrenal activation.The EMBO journal · 2020Observational
- The Redox Communication Network as a Regulator of Metabolism.Frontiers in physiology · 2020Review
- Lipidomics unveils lipid dyshomeostasis and low circulating plasmalogens as biomarkers in a monogenic mitochondrial disorder.JCI insight · 2019Article
- Oxidative Toxicology of Bleomycin: Role of the Extracellular Redox Environment.Current opinion in toxicology · 2019Article
- The Biological Clock: A Pivotal Hub in Non-alcoholic Fatty Liver Disease Pathogenesis.Frontiers in physiology · 2018Review
- Identification of the signals for glucose-induced insulin secretion in INS1 (832/13) β-cells using metformin-induced metabolic deceleration as a model.The Journal of biological chemistry · 2017Article
- The Reactive Species Interactome: Evolutionary Emergence, Biological Significance, and Opportunities for Redox Metabolomics and Personalized Medicine.Antioxidants & redox signaling · 2017Review
- Hyperinsulinemia: a Cause of Obesity?Current obesity reports · 2017Review
- Impact of gut hormone FGF-19 on type-2 diabetes and mitochondrial recovery in a prospective study of obese diabetic women undergoing bariatric surgery.BMC medicine · 2017Article
- Article
- The extracellular redox state modulates mitochondrial function, gluconeogenesis, and glycogen synthesis in murine hepatocytes.PloS one · 2015Article
- The Intra- or Extracellular Redox State Was Not Affected by a High vs. Low Glycemic Response Diet in Mice.PloS one · 2015Article
- Effects of thiol antioxidant β-mercaptoethanol on diet-induced obese mice.Life sciences · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Obesity and diabetes are caused by defects in metabolically sensitive tissues. Attention has been paid to insulin resistance as the key relevant pathosis, with a detailed focus on signal transduction pathways in metabolic tissues. Evidence exists to support an important role for each tissue in metabolic homeostasis and a potential causative role in both diabetes and obesity. The redox metabolome, that coordinates tissue responses and reflects shared control and regulation, is our focus. Consideration is given to the possibility that pathosis results from contributions of all relevant tissues, by virtue of a circulating communication system. Validation of this model would support simultaneous regulation of all collaborating metabolic organs through changes in the circulation, regardless of whether change was initiated exogenously or by a single organ.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.