ReviewThe Journal of allergy and clinical immunology2013
Atopic dermatitis results in intrinsic barrier and immune abnormalities: implications for contact dermatitis.
Review in The Journal of allergy and clinical immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 3 syntheses or guidelines pooled it, 233 citations in OpenAlex.
- Work-related and personal risk factors for occupational contact dermatitis: A systematic review of the literature with meta-analysis.Contact dermatitis · 2023Pooled it
- Integrative transcriptome-wide analysis of atopic dermatitis for drug repositioning.Communications biology · 2022Pooled it
- Food Avoidance Diets for Dermatitis.Current allergy and asthma reports · 2015Pooled it
- Long-Term Risk of Allergic Contact Dermatitis in Children With Atopic Respiratory Disease When They Reach Adulthood.Contact dermatitis · 2026Article
- The Mast Cell-Substance P Neuroimmune Axis in Allergic Contact Dermatitis and Atopic Dermatitis: Molecular Mechanisms and Pathophysiological Perspectives.Current issues in molecular biology · 2026Review
- Misregulation of T-box transcription factors drives BNP-NPR1 signalling underlying chronic itch.Nature communications · 2026Article
- The Role of and Therapeutic Strategies for Eosinophils in Atopic Dermatitis.Biomedicines · 2026Review
- Epithelial Barrier Dysfunction in Atopic Dermatitis, Allergic Contact Dermatitis, and Chronic Spontaneous Urticaria and its Therapeutic Implications.Current allergy and asthma reports · 2026Review
- Dendrobium officinale polysaccharides alleviate atopic dermatitis in vivo and in vitro through inhibition of inflammation and mitochondrial dysfunction.Journal of molecular histology · 2026Article
- Skin Barrier Dysfunction in Contact and Atopic Dermatitis: A Comparative Review.Allergy, asthma & immunology research · 2026Review
- Review
- The Role of Susceptibility in the Association Between Exposures and Occupational Contact Dermatitis: A Scoping Review.Contact dermatitis · 2026Article
- Atopic Dermatitis beyond Eczema: A Review on its Systemic Impact through Pruritus and Associated Comorbidities.Clinical reviews in allergy & immunology · 2025Review
- A Practical Approach to Chronic Hand Eczema.Dermatology and therapy · 2025Article
- PDE4 inhibitors in psoriasis therapy: current insights and future directions.Inflammopharmacology · 2025Review
- Wenqing Yin Attenuates the Allergic Contact Dermatitis Response by Inhibiting the JAK2/STAT1 and MAPK Signaling Pathways.Journal of inflammation research · 2025Article
- Yin-Hua Li-Shi Decoction Alleviated Atopic Dermatitis Through Regulating Th Cells Balance and Restoring Epithelial Barrier.Journal of inflammation research · 2025Article
- Irritant Contact Dermatitis Induced by Compound Clobetasol Propionate in a Patient with Undiagnosed Type 2 Diabetes Mellitus.Clinical, cosmetic and investigational dermatology · 2025Article
- Time to Occurrence of Incontinence-Associated Dermatitis: An Experimental Animal Study.Journal of inflammation research · 2025Article
- Differential Diagnosis of Irritant Versus Allergic Contact Dermatitis Based on Noninvasive Methods.Dermatology practical & conceptual · 2024Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Atopic dermatitis (AD), as well as irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD), are common skin diseases. These diseases are characterized by skin inflammation mediated by activated innate immunity or acquired immune mechanisms. Although AD, ICD, and ACD can be encountered in pure forms by allergists and dermatologists, patients with AD often present with increased frequency of ICD and ACD. Although a disturbed barrier alone could potentiate immune reactivity in patients with AD through increased antigen penetration, additional immune mechanisms might explain the increased susceptibility of atopic patients to ICD and ACD. This review discusses cellular pathways associated with increased skin inflammation in all 3 conditions and presents mechanisms that might contribute to the increased rate of ICD and ACD in patients with AD.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.