Evidence map›Paper›PMID 22938881›Full record

ReviewPhysical medicine and rehabilitation clinics of North America2012

Prevention and management of limb contractures in neuromuscular diseases.

Andrew J Skalsky, Craig M McDonald

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Physical medicine and rehabilitation clinics of North America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 65 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04677010 nacompletednot on this mapstarted 2021, after this paper: background citation

Cycle Exercise in Wheelchair Users With Muscular Dystrophy or Cerebral Palsy

TypeinterventionalSponsorRigshospitalet, DenmarkRan2021 to 2024Enrolled33ConditionsMuscular Dystrophies, Cerebral PalsyArmsCycle exercise
NCT06042907 completednot on this mapstarted 2023, after this paper: background citation

Development, Validation and Evaluation of the Feasibility of the Observational Risk Assessment of Contractures (Longitudinal Evaluation) Tool: The ORACLE Study

TypeobservationalSponsorBournemouth UniversityRan2023 to 2024Enrolled224ConditionsContracture, Joint Contracture
3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 2 syntheses or guidelines pooled it, 164 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Signs and symptoms of carriers of non-Journal of neuromuscular diseases · 2025
    Article
  12. Review
  13. Orthopaedic Management in Duchenne Muscular Dystrophy.Journal of the Pediatric Orthopaedic Society of North America · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Andrew J SkalskyRady Children's Hospital, Division of Pediatric Rehabilitation, MC 5096, 3020 Children's Way, University of California San Diego School of Medicine, San Diego, CA 92123, USA.
Craig M McDonald
Rady Children's Hospital-San Diego · USUniversity of California, Davis · US

Funding

Clinically Meaningful Outcomes for Duchenne Muscular Dystrophy Therapeutic TrialsR01AR061875 · NIAMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MCDONALD, CRAIG M. · 2011 to 2014
$1.3M
NIAMS NIH HHS R01 AR061875PHS HHS H133B0900001
6 · The paper itself

Abstract

Limb contractures are a common impairment in neuromuscular diseases. They contribute to increased disability from decreased motor performance, mobility limitations, reduced functional range of motion, loss of function for activities of daily living, and increased pain. The pathogenesis of contractures is multifactorial. Myopathic conditions are associated with more severe limb contractures compared with neuropathic disorders. Although the evidence supporting the efficacy of multiple interventions to improve range of motion in neuromuscular diseases in a sustained manner is lacking, there are generally accepted principles with regard to splinting, bracing, stretching, and surgery that help minimize the impact or disability from contractures.

Indexed as

Amyotrophic Lateral SclerosisArthrogryposisContractureHumansLower ExtremityMuscle Stretching ExercisesMuscular Atrophy, SpinalMuscular DystrophiesNeuromuscular DiseasesPostureRange of Motion, ArticularUpper Extremity

Identifiers

PMID22938881
PMCPMC3482407
OpenAlexW2079569594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.