ArticleJournal of the American Chemical Society2012
Single plasmonic nanoparticle tracking studies of solid supported bilayers with ganglioside lipids.
Article in Journal of the American Chemical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Understanding the Interaction Mechanism between the Epinephrine Neurotransmitter and Small Gold Nanoclusters (AuACS omega · 2024Article
- In silico investigation on interaction of small AgScientific reports · 2023Article
- Article
- β-Amyloid aggregation and heterogeneous nucleation.Protein science : a publication of the Protein Society · 2019Review
- In Situ Identification of Nanoparticle Structural Information Using Optical Microscopy.The journal of physical chemistry letters · 2018Article
- Membrane Fluidity Sensing on the Single Virus Particle Level with Plasmonic Nanoparticle Transducers.ACS sensors · 2017Article
- Impact of GMBiophysical journal · 2017Review
- GM1 Ganglioside Inhibits β-Amyloid Oligomerization Induced by Sphingomyelin.Angewandte Chemie (International ed. in English) · 2016Article
- Detection, counting, and imaging of single nanoparticles.Analytical chemistry · 2014Review
- Dark field nanoparticle tracking analysis for size characterization of plasmonic and non-plasmonic particles.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2014Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Single-particle tracking experiments were carried out with gold nanoparticle-labeled solid supported lipid bilayers (SLBs) containing increasing concentrations of ganglioside (GM(1)). The negatively charged nanoparticles electrostatically associate with a small percentage of positively charged lipids (ethyl phosphatidylcholine) in the bilayers. The samples containing no GM(1) show random diffusion in 92% of the particles examined with a diffusion constant of 4.3(±4.5) × 10(-9) cm(2)/s. In contrast, samples containing 14% GM(1) showed a mixture of particles displaying both random and confined diffusion, with the majority of particles, 62%, showing confined diffusion. Control experiments support the notion that the nanoparticles are not associating with the GM(1) moieties but instead most likely confined to regions in between the GM(1) clusters. Analysis of the root-mean-squared displacement plots for all of the data reveals decreasing trends in the confined diffusion constant and diameter of the confining region versus increasing GM(1) concentration. In addition, a linearly decreasing trend is observed for the percentage of randomly diffusing particles versus GM(1) concentration, which offers a simple, direct way to measure the percolation threshold for this system, which has not previously been measured. The percolation threshold is found to be 22% GM(1) and the confining diameter at the percolation threshold only ∼50 nm.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.