ArticleSchizophrenia research and treatment2011
Diffusion tensor imaging, structural connectivity, and schizophrenia.
Article in Schizophrenia research and treatment, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
16 citing papers in PubMed.
- A corollary discharge circuit in human speech.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Insights into myelin dysfunction in schizophrenia and bipolar disorder.World journal of psychiatry · 2022Review
- Brain Structural and Functional Connectivity: A Review of Combined Works of Diffusion Magnetic Resonance Imaging and Electro-Encephalography.Frontiers in human neuroscience · 2021Review
- Additive Burden of Abnormal Diffusivity in the Brain with Schizophrenia: A Diffusion Tensor Imaging Study with Public Neuroimaging Data.Psychiatry investigation · 2020Article
- Impaired illness awareness in schizophrenia and posterior corpus callosal white matter tract integrity.NPJ schizophrenia · 2019Article
- Enhanced temporal variability of amygdala-frontal functional connectivity in patients with schizophrenia.NeuroImage. Clinical · 2018Article
- Abnormal Rich-Club Organization Associated with Compromised Cognitive Function in Patients with Schizophrenia and Their Unaffected Parents.Neuroscience bulletin · 2017Article
- The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening.Frontiers in cell and developmental biology · 2017Review
- Neuroimaging for psychotherapy research: current trends.Psychotherapy research : journal of the Society for Psychotherapy Research · 2015Review
- Impaired rich club connectivity in unaffected siblings of schizophrenia patients.Schizophrenia bulletin · 2014Article
- Cortical information flow during inferences of agency.Frontiers in human neuroscience · 2014Article
- What is Going on in Psychiatry When Nothing Seems to Happen?Frontiers in psychiatry · 2013Review
- High-frequency neural oscillations and visual processing deficits in schizophrenia.Frontiers in psychology · 2013Review
- Functional neuroimaging and schizophrenia: a view towards effective connectivity modeling and polygenic risk.Dialogues in clinical neuroscience · 2013Review
- The development of psychotic disorders in adolescence: a potential role for hormones.Hormones and behavior · 2013Review
- A review of magnetic resonance imaging and diffusion tensor imaging findings in mild traumatic brain injury.Brain imaging and behavior · 2012Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
A fundamental tenet of the "disconnectivity" theories of schizophrenia is that the disorder is ultimately caused by abnormal communication between spatially disparate brain structures. Given that the white matter fasciculi represent the primary infrastructure for long distance communication in the brain, abnormalities in these fiber bundles have been implicated in the etiology of schizophrenia. Diffusion tensor imaging (DTI) is a magnetic resonance imaging (MRI) technique that enables the visualization of white matter macrostructure in vivo, and which has provided unprecedented insight into the existence and nature of white matter abnormalities in schizophrenia. The paper begins with an overview of DTI and more commonly used diffusion metrics and moves on to a brief review of the schizophrenia literature. The functional implications of white matter abnormalities are considered, particularly with respect to myelin's role in modulating the transmission velocity of neural discharges. The paper concludes with a speculative hypothesis about the relationship between gray and white matter abnormalities associated with schizophrenia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.