Evidence map›Paper›PMID 22937250›Full record

ArticleAutism research and treatment2011

The broader autism phenotype and its implications on the etiology and treatment of autism spectrum disorders.

Jennifer Gerdts, Raphael Bernier

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Autism research and treatment, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03432832 (Emotion Awareness and Skills Enhancement), which is not on this map. Cited by 75 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03432832 nacompletednot on this mapstarted 2018, after this paper: background citation

Emotion Awareness and Skills Enhancement (EASE) Program: A Clinical Trial

TypeinterventionalSponsorUniversity of PittsburghRan2018 to 2024Enrolled113ConditionsAutism Spectrum DisorderArmsEASE, Supportive Therapy
3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jennifer GerdtsDepartment of Psychology, University of Washington, Seattle, WA 98195, USA.
Raphael Bernier
University of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of autism-related traits has been well documented in undiagnosed family members of individuals with autism spectrum disorder (ASD). The most common finding is mild impairments in social and communication skills that are similar to those shown by individuals with autism, but exhibited to a lesser degree. Termed the broader autism phenotype (BAP), these traits suggest a genetic liability for autism-related traits in families. Genetic influence in autism is strong, with identical twins showing high concordance for the diagnosis and related traits and approximately 20% of all ASD cases having an identified genetic mechanism. This paper highlights the studies conducted to date regarding the BAP and considers the implications of these findings for the etiology and treatment of ASD.

Identifiers

PMID22937250
PMCPMC3420416
OpenAlexW2095109051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.