ReviewNeurocritical care2012
Emergency neurological life support: intracranial hypertension and herniation.
Review in Neurocritical care, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Hypertonic saline versus other intracranial pressure-lowering agents for people with acute traumatic brain injury.The Cochrane database of systematic reviews · 2020Pooled it
- Hypertonic saline versus other intracranial pressure-lowering agents for people with acute traumatic brain injury.The Cochrane database of systematic reviews · 2019Pooled it
- Pediatric diabetic ketoacidosis and cerebral oedema: a systematic review.Annals of pediatric endocrinology & metabolism · 2025Article
- Dynamic Optic Nerve Sheath Diameter (ONSD) guided management of raised intracranial pressure in pediatric acute liver failure.Hepatology international · 2021Article
- The Medical Management of Cerebral Edema: Past, Present, and Future Therapies.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2019Review
- The Clock Is Ticking - Brain Atrophy in Case of Acute Trauma?Korean journal of neurotrauma · 2019Article
- The Neurological Wake-up Test-A Role in Neurocritical Care Monitoring of Traumatic Brain Injury Patients?Frontiers in neurology · 2017Review
- The critical care management of poor-grade subarachnoid haemorrhage.Critical care (London, England) · 2016Article
- Cardiac emergencies in neurosurgical patients.BioMed research international · 2015Review
- Blood pressure levels and prognosis of intracranial trauma patients with cognitive dysfunction.Pakistan journal of medical sciences · 2014Article
- Imaging acute complications in cancer patients: what should be evaluated in the emergency setting?Cancer imaging : the official publication of the International Cancer Imaging Society · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sustained intracranial hypertension and acute brain herniation are "brain codes," signifying catastrophic neurological events that require immediate recognition and treatment to prevent irreversible injury and death. As in cardiac arrest, evidence supports the organized implementation of a stepwise management algorithm. Because there are multiple etiologies and many treatments that can potentially reverse cerebral herniation, intracranial hypertension and herniation was chosen as an Emergency Neurological Life Support (ENLS) protocol.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.