ArticleProceedings of the National Academy of Sciences of the United States of America2013
Interdisciplinary approaches to understanding disease emergence: the past, present, and future drivers of Nipah virus emergence.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
74 citing papers in PubMed, 2 syntheses or guidelines pooled it, 157 citations in OpenAlex.
- Nairobi Sheep Disease Virus: A Historical and Epidemiological Perspective.Frontiers in veterinary science · 2020Pooled it
- Agricultural land-uses consistently exacerbate infectious disease risks in Southeast Asia.Nature communications · 2019Pooled it
- Epidemiology of pathogenic enterobacteria in humans, livestock, and peridomestic rodents in rural Madagascar.PloS one · 2014Trial
- One Health Insights From Pteropus medius: Nipah Virus Spillover, Microbiota, and Antimicrobial Resistance.MicrobiologyOpen · 2026Review
- Linking prey biomass and Neanderthal population in a challenging upland landscape in the Late Pleistocene: the upper valley of the Lozoya River (Spain).Landscape ecology · 2026Article
- Emerging Vector-Borne Nipah Virus Infection: Unexplored Hazards, Diagnostic Challenges, and the Potential of Phytomedicine-Based Therapeutics.Current pharmaceutical design · 2026Review
- Gendered male and high-income country authors dominate publication at a One Health research organization.PloS one · 2026Article
- Toward Relationality in Infectious Disease Research.Open forum infectious diseases · 2025Article
- Mapping global risk of bat and rodent borne disease outbreaks to anticipate emerging threats.Scientific reports · 2025Article
- From Bat to Worse: The Pivotal Role of Bats for Viral Zoonosis.Microbial biotechnology · 2025Review
- One Health in a globalized world: challenges and responses to zoonotic threats.Global bioethics = Problemi di bioetica · 2025Article
- Improving biosafety measures in high containment laboratories and patient care: a systematic analysis ofFrontiers in public health · 2025Article
- Ethical issues in Nipah virus control and research: addressing a neglected disease.Journal of medical ethics · 2024Article
- The impact of anthropogenic climate change on pediatric viral diseases.Pediatric research · 2024Review
- Building a pathway to One Health surveillance and response in Asian countries.Science in One Health · 2024Review
- Reservoir population ecology, viral evolution and the risk of emerging infectious disease.Proceedings. Biological sciences · 2022Article
- Article
- Climate Anomalies and Spillover of Bat-Borne Viral Diseases in the Asia-Pacific Region and the Arabian Peninsula.Viruses · 2022Article
- Ecological Barrier Deterioration Driven by Human Activities Poses Fatal Threats to Public Health due to Emerging Infectious Diseases.Engineering (Beijing, China) · 2022Review
- Henipaviruses-A constant threat to livestock and humans.PLoS neglected tropical diseases · 2022Review
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Emerging infectious diseases (EIDs) pose a significant threat to human health, economic stability, and biodiversity. Despite this, the mechanisms underlying disease emergence are still not fully understood, and control measures rely heavily on mitigating the impact of EIDs after they have emerged. Here, we highlight the emergence of a zoonotic Henipavirus, Nipah virus, to demonstrate the interdisciplinary and macroecological approaches necessary to understand EID emergence. Previous work suggests that Nipah virus emerged due to the interaction of the wildlife reservoir (Pteropus spp. fruit bats) with intensively managed livestock. The emergence of this and other henipaviruses involves interactions among a suite of anthropogenic environmental changes, socioeconomic factors, and changes in demography that overlay and interact with the distribution of these pathogens in their wildlife reservoirs. Here, we demonstrate how ecological niche modeling may be used to investigate the potential role of a changing climate on the future risk for Henipavirus emergence. We show that the distribution of Henipavirus reservoirs, and therefore henipaviruses, will likely change under climate change scenarios, a fundamental precondition for disease emergence in humans. We assess the variation among climate models to estimate where Henipavirus host distribution is most likely to expand, contract, or remain stable, presenting new risks for human health. We conclude that there is substantial potential to use this modeling framework to explore the distribution of wildlife hosts under a changing climate. These approaches may directly inform current and future management and surveillance strategies aiming to improve pathogen detection and, ultimately, reduce emergence risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.