ArticleThe journal of headache and pain2012
Impact of sex hormonal changes on tension-type headache and migraine: a cross-sectional population-based survey in 2,600 women.
Article in The journal of headache and pain, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Sex-specific management of migraine a systematic review and consensus statement from the European Headache Federation (EHF).The journal of headache and pain · 2026Pooled it
- Systematic review of late-onset aura related to migraine: an overlooked phenomenon.Acta neurologica Belgica · 2025Pooled it
- The Effect of Hamstring Relaxation Program on Headache, Pressure Pain Threshold, and Range of Motion in Patients with Tension Headache: A Randomized Controlled Trial.International journal of environmental research and public health · 2021Trial
- Sex-specific considerations in migraine therapy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Review
- Causal proteomic insights into drug target discovery for tension-type headache.The journal of headache and pain · 2025Article
- Association of migraine and vasomotor symptom severity and duration among naturally menopausal women in Nurses' Health Study II.Menopause (New York, N.Y.) · 2025Article
- The Impact of Pregnancy on Functional Neurological Disorder (FND).European journal of neurology · 2025Article
- Analysis and 15-Year Projections of the Global Burden of Tension-Type Headache by Sex from 1990 to 2021: A Systematic Review of GBD 2021 Data.Journal of pain research · 2025Article
- [Temporal trend of the global prevalence rate of tension-type headache in children and adolescents in 1990-2021].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
- International standard of Traditional Chinese Medicine Techniques: Traditional Chinese Medicine guidelines for acute primary headache (2022).Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024Article
- Pure menstrual tension-type headache: demonstration of its existence.Acta neurologica Belgica · 2024Observational
- Associations between environmental perchlorate, nitrate, and thiocyanate exposure and severe headache or migraine: a cross-sectional, population-based analysis.Frontiers in neurology · 2024Article
- The role of purity and frequency in the classification of perimenstrual headache.BMC neurology · 2023Article
- Relationships between headache frequency, disability, and disability-related unemployment among adults with migraine.Journal of managed care & specialty pharmacy · 2023Article
- Is there any association between migraine headache and polycystic ovary syndrome (PCOS)? A review article.Molecular biology reports · 2022Review
- Medicines for headache before and during pregnancy: a retrospective cohort study (ATENA study).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Perceptions of Modulatory Factors in Migraine and Epilepsy: A Multicenter Study.Frontiers in neurology · 2021Article
- Identifying Chinese Medicine Patterns of Tension-Type Headache and Understanding Its Subgroups.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Familial analysis reveals rare risk variants for migraine in regulatory regions.Neurogenetics · 2020Article
- Sex Differences of Migraine: Results of a Nationwide Home-based Study in Turkey.Noro psikiyatri arsivi · 2020Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex hormones have some implications on headaches. The objective of the study was to investigate the effects of hormonal changes comparatively on tension-type headache (TTH) and migraine, in a population-based sample. A nationwide face-to-face prevalence study was conducted using a structured electronic questionnaire. 54.3 % of the migraineurs reported that the probability of experiencing headache during menstruation was high, whereas 3.9 % had headache only during menstruation. Forward logistic regression analysis revealed that menstruation was a significant trigger for migraine in comparison to TTH. On the other hand, nearly double the number of TTH sufferers reported "pure menstrual headache" compared to migraineurs (p = 0.02). Menstrual headaches caused significantly higher MIDAS grades. One-third of the definite migraineurs reported improvement during pregnancy and oral contraceptives significantly worsened migraine. Menopause had a slight improving effect on migraine compared to TTH. Sex hormonal changes have major impacts particularly on migraine; however, the effects of hormonal fluctuations on TTH should not be underestimated.
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