Evidence map›Paper›PMID 22935553›Full record

ReviewJournal of child neurology2012

Autoimmune encephalitis in children.

Thaís Armangue, Mar Petit-Pedrol, Josep Dalmau

Open access · greenAbstract readReview
In one paragraph

Review in Journal of child neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 209 citations in OpenAlex.

  1. [18F]FDG brain PET and clinical symptoms in different autoantibodies of autoimmune encephalitis: a systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Pooled it
  2. Review
  3. Spectrum of Clinical and Imaging Features of Children With GFAP Astrocytopathy.Neurology(R) neuroimmunology & neuroinflammation · 2025
    Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Observational
  10. Autoimmune Encephalitis Due to COVID-19 in a Young Patient.Iranian journal of child neurology · 2023
    Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Pediatric autoimmune encephalitis: Recognition and diagnosis.Neurology(R) neuroimmunology & neuroinflammation · 2020
    Observational

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Thaís ArmangueInstitut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Service of Neurology, Hospital Clínic, University of Barcelona, Barcelona, Spain.
Mar Petit-Pedrol
Josep Dalmau
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESInstitució Catalana de Recerca i Estudis Avançats · ESUniversitat de Barcelona · ES

Funding

Immunity to Brain Ma Proteins--A Remote Effect of CancerR01CA089054 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DALMAU, JOSEP O. · 2001 to 2011
$2.1M
Paraneoplastic Disorders of the CNS: Autoantigen ProfilingR01NS077851 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DALMAU, JOSEP O. · 2011 to 2015
$1.9M
Autoimmunity Against Novel Antigens in Neuropsychiatric DysfunctionR01MH094741 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI BALICE-GORDON, RITA J., DALMAU, JOSEP O. · 2011 to 2014
$1.3M
NCI NIH HHS R01 CA089054NCI NIH HHS R01CA89054NIMH NIH HHS R01 MH094741NIMH NIH HHS R01MH094741NINDS NIH HHS R01 NS077851NINDS NIH HHS R01NS077851
6 · The paper itself

Abstract

The causes of encephalitis are numerous, and extensive investigations for infectious agents and other etiologies are often negative. The discovery that many of these encephalitis are immune mediated has changed the approach to the diagnosis and treatment of these disorders. Moreover, the broad spectrum of symptoms including, psychosis, catatonia, alterations of behavior and memory, seizures, abnormal movements, and autonomic dysregulation usually requires a multidisciplinary treatment approach. This review focuses in several forms of encephalitis that occur in children, and for which an autoimmune etiology has been demonstrated (eg, anti-N-methyl-d-aspartate receptor encephalitis) or is strongly suspected (eg, Rasmussen encephalitis, limbic encephalitis, opsoclonus-myoclonus). The authors also review several disorders that may be immune mediated, such as the rapid onset obesity with hypothalamic dysfunction, hypoventilation and autonomic dysregulation (ROHHAD) syndrome and some encephalopathies with fever and status epilepticus. Recognition of novel immune-mediated encephalitis is important because some of these disorders are highly responsive to immunotherapy.

Indexed as

Brain DiseasesChildEncephalitisHashimoto DiseaseHumansImmunotherapyPediatrics

Identifiers

PMID22935553
PMCPMC3705178
OpenAlexW2053911870

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.