Evidence map›Paper›PMID 22935331›Full record

ArticleBMC public health2012

Determinants of antiretroviral therapy adherence in northern Tanzania: a comprehensive picture from the patient perspective.

Ramsey A Lyimo, Marijn de Bruin, Jossy van den Boogaard, Harm J Hospers, André van der Ven, Declare Mushi

Abstract read
In one paragraph

Article in BMC public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  7. Determinants of antiretroviral therapy adherence among transgender women in South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ramsey A LyimoKilimanjaro Clinical Research Institute, Kilimanjaro Christian Medical Centre, P,O,Box 2236, Moshi, Tanzania. rlyimo7@yahoo.com
Marijn de Bruin
Jossy van den Boogaard
Harm J Hospers
André van der Ven
Declare Mushi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo design effective, tailored interventions to support antiretroviral therapy (ART) adherence, a thorough understanding of the barriers and facilitators of ART adherence is required. Factors at the individual and interpersonal level, ART treatment characteristics and health care factors have been proposed as important adherence determinants.

methodsTo identify the most relevant determinants of adherence in northern Tanzania, in-depth interviews were carried out with 61 treatment-experienced patients from four different clinics. The interviews were ad-verbatim transcribed and recurrent themes were coded.

resultsCoding results showed that the majority of patients had basic understanding of adherence, but also revealed misconceptions about taking medication after alcohol use. Adherence motivating beliefs were the perception of improved health and the desire to live like others, as well as the desire to be a good parent. A de-motivating belief was that stopping ART after being prayed for was an act of faith. Facilitators of adherence were support from friends and family, and assistance of home based care (HBC) providers. Important barriers to ART adherence were the use of alcohol, unavailability of food, stigma and disclosure concerns, and the clinics dispensing too few pills. Strategies recommended by the patients to improve adherence included better Care and Treatment Centre (CTC) services, recruitment of patients to become Home Based Care ( HBC) providers, and addressing the problem of stigma through education.

conclusionThis study underscores the importance of designing tailored, patient-centered adherence interventions to address challenges at the patient, family, community and health care level.

Indexed as

AdolescentAdultAnti-HIV AgentsDrug MonitoringFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHumansInterviews as TopicMaleMedication AdherenceMiddle AgedMotivationSocial SupportTanzaniaYoung AdultAnti-HIV Agents

Identifiers

PMID22935331
PMCPMC3488585

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.