Evidence map›Paper›PMID 22935298›Full record

ArticleClinical and translational allergy2012

Control of Allergic Rhinitis and Asthma Test (CARAT) can be used to assess individual patients over time.

Joao A Fonseca, Luis Nogueira-Silva, Mario Morais-Almeida, Ana Sa-Sousa, Luis F Azevedo, Jose Ferreira, Manuel Branco-Ferreira, Rodrigo Rodrigues-Alves, Antonio Bugalho-Almeida, Jean Bousquet

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Article in Clinical and translational allergy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Observational
  10. Observational
  11. Article
  12. Article
  13. Article
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  16. Article
  17. Observational
  18. Control of Allergic Rhinitis and Asthma Test (CARAT): dissemination and applications in primary care.Primary care respiratory journal : journal of the General Practice Airways Group · 2013
    Article
  19. Assessment of disease control in allergic rhinitis.Clinical and translational allergy · 2013
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joao A FonsecaFaculdade de Medicina da Universidade do Porto, Health Information and Decision Sciences Department, Porto, Portugal. fonseca.ja@gmail.com.
Luis Nogueira-Silva
Mario Morais-Almeida
Ana Sa-Sousa
Luis F Azevedo
Jose Ferreira
Manuel Branco-Ferreira
Rodrigo Rodrigues-Alves
Antonio Bugalho-Almeida
Jean Bousquet

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelled

backgroundThe Control of Allergic Rhinitis and Asthma Test (CARAT10) has been proposed as the first tool to implement the Allergic Rhinitis and its Impact on Asthma initiative guidelines in clinical practice. To serve this purpose, it must have adequate properties to assess the control of an individual over time. This study aimed to prospectively assess the test-retest reliability, responsiveness and longitudinal validity of CARAT10.

methodsAdults with asthma and allergic rhinitis were enrolled at 4 outpatient clinics of Portuguese central hospitals. At each of the two visits, 4 to 6 weeks apart, patients filled out CARAT10 and additional questionnaires, followed by a medical evaluation blinded to the questionnaires' answers.

resultsFrom the 62 patients included, 51 patients completely filled out CARAT10 at both visits. The test-retest reliability, computed as an intra-class correlation coefficient, was 0.82. Regarding responsiveness, a significant change (p = 0.002) of CARAT10 score in clinically unstable patients was observed (95%CI -5.08; -1.31) and the Guyatt's responsiveness index was 1.54. As for the longitudinal validity assessment, the correlation coefficients of the changes of CARAT10 scores with those of ACQ5 and symptoms VAS ranged from 0.49 to 0.65, while with the physician assessment of control they ranged from 0.31 to 0.41.

conclusionCARAT10 has good test-retest reliability, responsiveness and longitudinal validity. It can be used to assess control of allergic rhinitis and asthma, both to compare groups in clinical studies and to evaluate individual patients in clinical practice.

Identifiers

PMID22935298
PMCPMC3520832

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.