Evidence map›Paper›PMID 22934961›Full record

SynthesisAlcoholism, clinical and experimental research2013

A systematic review and meta-analysis of alcohol consumption and injury risk as a function of study design and recall period.

Cornelia Zeisser, Tim R Stockwell, Tanya Chikritzhs, Cheryl Cherpitel, Yu Ye, Christian Gardner

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Alcoholism, clinical and experimental research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Do socioeconomic status, race and ethnicity modify the relationship between alcohol use and unintentional injury mortality?Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2025
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  9. Review
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  13. Predictors of High Resource Consumption in Alcohol Intoxicated Patients in the Emergency Department.International journal of environmental research and public health · 2020
    Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cornelia ZeisserCentre for Addictions Research of BC, Victoria, BC, Canada. czeisser@uvic.ca
Tim R Stockwell
Tanya Chikritzhs
Cheryl Cherpitel
Yu Ye
Christian Gardner

Funding

TREND &STRUCTURE OF ALCOHOL DEPENDENCE--GENERAL POPULATION 1990 SURVEY DATAP50AA005595 · NIAAA · WESTERN CONSORTIUM FOR PUBLIC HEALTH · PI LUI, CAMILLIA K. · 1985 to 2025
$34.1M
Cross-National Analysis of Alcohol & InjuryR01AA013750 · NIAAA · PUBLIC HEALTH INSTITUTE · PI CHERPITEL, CHERYL J · 2002 to 2018
$4.4M
NIAAA NIH HHS P50 AA005595NIAAA NIH HHS R01 AA013750
6 · The paper itself

Abstract

backgroundIt is well established that alcohol consumption is associated with an increased risk of injury. This systematic review and meta-analysis addresses important methodological issues commonly encountered in the alcohol and injury field by delineating the effect of study design and alcohol consumption recall period on effect size magnitude and by conducting gender-specific analyses.

methodsWe performed meta-analyses using random-effect models. Data sources were peer-reviewed studies on alcohol and injury from 1970 to 2009 from MEDLINE, PsychInfo, and on-line journals. Case-control or case-crossover emergency department (ED) studies reporting injury risk from alcohol consumption 6 hours before injury were included.

resultsThe overall odds of injury were 2.799 (2.214 to 3.538, p < 0.001). For case-crossover studies, the odds were 3.815 (2.646 to 5.499, p < 0.001); for ED case-control studies, the odds were 1.977 (1.385 to 2.821, p < 0.001); and for population case-control designs, the odds were 3.145 (1.583 to 6.247, p < 0.005). The "usual frequency" recall period yielded an odds ratio of 4.235 (2.541 to 7.057, p < 0.001), compared to 2.320 (1.789 to 3.008, p < 0.001) for all other methods. There were significant differences in odds ratio magnitude when comparing studies by design and recall period. Females had higher odds of injury than males, 2.285 (1.361 to 3.836, p < 0.005) versus 1.071 (0.715 to 1.605, p = 0.737).

conclusionsStudy design and alcohol consumption recall period have significant effects on effect size magnitude in estimating the risk of injury from alcohol consumption 6 hours prior to injury. For the "usual frequency" case-crossover design, significant moderator effects were found, resulting in overestimates of injury risk from alcohol. ED case-crossover designs tend to overestimate risk, and ED case-control designs tend to underestimate. We provide recommendations for future ED research.

Indexed as

Mental RecallResearch DesignAlcohol DrinkingCase-Control StudiesCross-Over StudiesHumansRisk FactorsTime FactorsWounds and Injuries

Identifiers

PMID22934961
PMCPMC3515689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.