Evidence map›Paper›PMID 22934662›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2013

The relationship between large cavum septum pellucidum and antisocial behavior, callous-unemotional traits and psychopathy in adolescents.

Stuart F White, Sarah Brislin, Stephen Sinclair, Katherine A Fowler, Kayla Pope, R James R Blair

Open access · greenAbstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

  1. Callous and Unemotional Traits as Precursors to the Development of Female Psychopathy.International journal of environmental research and public health · 2023
    Pooled it
  2. Article
  3. Article
  4. The basolateral amygdala to lateral septum circuit is critical for regulating social novelty in mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  5. Review
  6. Psychopathy.Nature reviews. Disease primers · 2021
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. The neurobiology of psychopathic traits in youths.Nature reviews. Neuroscience · 2013
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Stuart F WhiteUnit on Affective Cognitive Neuroscience, National Institute of Mental Health, NIH, Bethesda, MD, USA. whitesf@mail.nih.gov
Sarah Brislin
Stephen Sinclair
Katherine A Fowler
Kayla Pope
R James R Blair
National Institute of Mental Health · USNational Institutes of Health · US

Funding

Emotional Dysfunction and Childhood Behavioral DisturbanceZIAMH002860 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI BLAIR, JAMES R · 2009 to 2016
$9.5M
Intramural NIH HHS Z99 MH999999
6 · The paper itself

Abstract

backgroundThe presence of a large cavum septum pellucidum (CSP) has been previously associated with antisocial behavior/psychopathic traits in an adult community sample.

aimsThe current study investigated the relationship between a large CSP and symptom severity in disruptive behavior disorders (DBD; conduct disorder and oppositional defiant disorder).

methodStructural MRI scans of youth with DBDs (N = 32) and healthy comparison youth (N = 27) were examined for the presence of a large CSP and if this was related to symptom severity.

resultsReplicating previous results, a large CSP was associated with DBD diagnosis, proactive aggression, and level of psychopathic traits in youth. However, the presence of a large CSP was unrelated to aggression or psychopathic traits within the DBD sample.

conclusionsEarly brain mal-development may increase the risk of a DBD diagnosis, but does not mark a particularly severe form of DBD within patients receiving these diagnoses.

Indexed as

Image Interpretation, Computer-AssistedMagnetic Resonance ImagingAggressionAntisocial Personality DisorderAttention Deficit and Disruptive Behavior DisordersConduct DisorderEmpathyHumansOrgan SizePersonality AssessmentPersonality InventoryPsychometricsReference ValuesRisk FactorsSeptum PellucidumStatistics as Topic

Identifiers

PMID22934662
PMCPMC3514613
OpenAlexW2125641194

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.