ArticleAnnual review of genetics2012
Genetics of reproduction and regulation of honeybee (Apis mellifera L.) social behavior.
Article in Annual review of genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
42 citing papers in PubMed, 102 citations in OpenAlex.
- Regulatory RNA Patterns Associated with Bee Evolution Should Be Interpreted with Caution, but Correlational Studies Should Not Be Entirely Dismissed.Genome biology and evolution · 2026Article
- Susceptibility to the Neonicotinoid Pesticide Imidacloprid Is Linked to Life History Regulation in Honey Bees (Apis mellifera L.).Molecular ecology · 2026Article
- Deformed wing virus affects foraging success and foraging specialization of honeybee workers.Scientific reports · 2025Article
- BalancingInternational journal for parasitology. Parasites and wildlife · 2025Article
- The intensity of the transcriptional response varies across infection with distinct viral strains in an insect host.BMC genomics · 2025Article
- Combining Individual-Based Radio-Tracking With Whole-Genome Sequencing Data Reveals Candidate for Genetic Basis of Partial Migration in a Songbird.Ecology and evolution · 2025Article
- Molecular Basis of Eusocial Complexity: The Case of Worker Reproductivity in Bees.Genome biology and evolution · 2024Article
- Dedicated developmental programing for group-supporting behaviors in eusocial honeybees.Science advances · 2024Article
- Article
- Harvester ant colonies differ in collective behavioural plasticity to regulate water loss.Royal Society open science · 2023Article
- Honey Bee Colonies (Insects · 2023Article
- Behavioral genetics and genomics: Mendel's peas, mice, and bees.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Single-cell transcriptomic analysis of honeybee brains identifies vitellogenin as caste differentiation-related factor.iScience · 2022Article
- Context-dependent influence of threat on honey bee social network dynamics and brain gene expression.The Journal of experimental biology · 2022Article
- Honey bee genetics shape the strain-level structure of gut microbiota in social transmission.Microbiome · 2021Article
- Societies to genes: can we get there from here?Genetics · 2021Article
- Comparative transcriptomic analysis of the mechanisms underpinning ageing and fecundity in social insects.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Tachykinin signaling inhibits task-specific behavioral responsiveness in honeybee workers.eLife · 2021Article
- A-to-I RNA editing in honeybees shows signals of adaptation and convergent evolution.iScience · 2021Article
- Expression of methyl farnesoate epoxidase (mfe) and juvenile hormone esterase (jhe) genes and their relation to social organization in the stingless bee Melipona interrupta (Hymenoptera: Apidae).Genetics and molecular biology · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Honeybees form complex societies with a division of labor for reproduction, nutrition, nest construction and maintenance, and defense. How does it evolve? Tasks performed by worker honeybees are distributed in time and space. There is no central control over behavior and there is no central genome on which selection can act and effect adaptive change. For 22 years, we have been addressing these questions by selecting on a single social trait associated with nutrition: the amount of surplus pollen (a source of protein) that is stored in the combs of the nest. Forty-two generations of selection have revealed changes at biological levels extending from the society down to the level of the gene. We show how we constructed this vertical understanding of social evolution using behavioral and anatomical analyses, physiology, genetic mapping, and gene knockdowns. We map out the phenotypic and genetic architectures of food storage and foraging behavior and show how they are linked through broad epistasis and pleiotropy affecting a reproductive regulatory network that influences foraging behavior. This is remarkable because worker honeybees have reduced reproductive organs and are normally sterile; however, the reproductive regulatory network has been co-opted for behavioral division of labor.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.