ArticleCase reports in pulmonology2012
Diffuse alveolar hemorrhage: a rare life-threatening condition in systemic lupus erythematosus.
Article in Case reports in pulmonology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- A Rare Presentation of Systemic Lupus Erythematosus (SLE) With Hemoptysis and Hematuria: A Case Report.Cureus · 2024Article
- Article
- A Rare Case of Systemic Lupus Erythematosus With Diffuse Alveolar Hemorrhage and Guillain-Barre Syndrome.Cureus · 2023Article
- Varicella-zoster virus pneumonia presenting as diffuse alveolar haemorrhage in a patient with a history of systemic lupus erythematosus.BMJ case reports · 2022Article
- Diagnosis and management of lung involvement in systemic lupus erythematosus and Sjögren's syndrome: a literature review.Therapeutic advances in musculoskeletal disease · 2021Review
- Systemic lupus erythematosus and diffuse alveolar hemorrhage, etiology and novel treatment strategies.Lupus · 2020Review
- Chance, genetics, and the heterogeneity of disease and pathogenesis in systemic lupus erythematosus.Seminars in immunopathology · 2014Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diffuse alveolar hemorrhage (DAH) is a rare life-threatening complication in systemic lupus erythematosus (SLE) associated with high mortality rates. DAH is more common in women, and mean age of onset is around 30 years. It mostly occurs in patients with established diagnosis of SLE but can be the initial presentation of lupus in approximately 20%. DAH should be suspected in lupus patient presenting with new pulmonary infiltrates, decline in hemoglobin, hemoptysis, dyspnea, hypoxemia, and increase in carbon monoxide diffusion capacity. Radiographic evidence of bilateral pulmonary alveolar infiltrates that are usually perihilar or basilar with sparing of apices is seen. DAH can often mimic clinically and radiologically severe pneumonia or ARDS. Treatment includes high-dose corticosteroids, cyclophosphamide, and plasmapheresis. We report a case of diffuse alveolar hemorrhage complicating SLE flare-up in a male patient.
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Registered trials
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