ArticleFrontiers in physiology2012
The importance of modeling epileptic seizure dynamics as spatio-temporal patterns.
Article in Frontiers in physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Predicting Surgery Targets in Temporal Lobe Epilepsy through Structural Connectome Based Simulations.PLoS computational biology · 2015Trial
- Seizure recruitment properties are dependent upon dynamotype: A modeling study.PLoS computational biology · 2026Article
- Altered Temporospatial Variability of Dynamic Amplitude of Low-Frequency Fluctuation in Children with Autism Spectrum Disorder.Journal of autism and developmental disorders · 2026Article
- Passive neuromodulation: an energy-driven mechanism for closed-loop suppression of epileptic seizures.bioRxiv : the preprint server for biology · 2026Article
- Virtual epilepsy patient cohort: Generation and evaluation.PLoS computational biology · 2025Article
- Optimising anti-seizure medication timing using a dynamic network model of seizure rhythms.Frontiers in network physiology · 2025Article
- Predictive modeling of evoked intracranial EEG response to medial temporal lobe stimulation in patients with epilepsy.Communications biology · 2024Article
- Editorial: Reviews in networks in the brain system.Frontiers in network physiology · 2024Article
- Dynamical Network Models From EEG and MEG for Epilepsy Surgery-A Quantitative Approach.Frontiers in neurology · 2022Review
- Adiabatic dynamic causal modelling.NeuroImage · 2021Article
- Cross-Scale Causality and Information Transfer in Simulated Epileptic Seizures.Entropy (Basel, Switzerland) · 2021Article
- Perturbations both trigger and delay seizures due to generic properties of slow-fast relaxation oscillators.PLoS computational biology · 2021Article
- Patient-Specific Network Connectivity Combined With a Next Generation Neural Mass Model to Test Clinical Hypothesis of Seizure Propagation.Frontiers in systems neuroscience · 2021Article
- Domino-like transient dynamics at seizure onset in epilepsy.PLoS computational biology · 2020Article
- The Role of Excitability and Network Structure in the Emergence of Focal and Generalized Seizures.Frontiers in neurology · 2020Article
- The role that choice of model plays in predictions for epilepsy surgery.Scientific reports · 2019Article
- Seizure prediction - ready for a new era.Nature reviews. Neurology · 2018Review
- Classifying dynamic transitions in high dimensional neural mass models: A random forest approach.PLoS computational biology · 2018Article
- Network dynamics in the healthy and epileptic developing brain.Network neuroscience (Cambridge, Mass.) · 2018Article
- Localization of Epileptogenic Zone With the Correction of Pathological Networks.Frontiers in neurology · 2018Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The occurrence of seizures is the common feature across the spectrum of epileptic disorders. We describe how the use of mechanistic neural population models leads to novel insight into the dynamic mechanisms underlying two important types of epileptic seizures. We specifically stress the need for a spatio-temporal description of the rhythms to deal with the complexity of the pathophenotype. Adapted to functional and structural patient data, the macroscopic models may allow a patient-specific description of seizures and prediction of treatment outcome.
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Registered trials
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