ArticleRadiology and oncology2012
A comparison of virtual touch tissue quantification and digital rectal examination for discrimination between prostate cancer and benign prostatic hyperplasia.
Article in Radiology and oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Value of shear wave elastography in discriminating malignant and benign breast lesions: A meta-analysis.Medicine · 2017Pooled it
- Prostate Cancer Detection Using 3-D Shear Wave Elasticity Imaging.Ultrasound in medicine & biology · 2021Article
- Characterisation of Prostate Lesions Using Transrectal Shear Wave Elastography (SWE) Ultrasound Imaging: A Systematic Review.Cancers · 2021Review
- A parametric evaluation of shear wave speeds estimated with time-of-flight calculations in viscoelastic media.The Journal of the Acoustical Society of America · 2020Article
- Why Are Viscosity and Nonlinearity Bound to Make an Impact in Clinical Elastographic Diagnosis?Sensors (Basel, Switzerland) · 2020Review
- Principles of ultrasound elastography.Abdominal radiology (New York) · 2018Review
- Benign and malignant breast lesions identification through the values derived from shear wave elastography: evidence for the meta-analysis.Oncotarget · 2017Article
- Role of Acoustic Radiation Force Impulse (ARFI) Elastography in Determination of Severity of Benign Prostate Hyperplasia.Medical science monitor : international medical journal of experimental and clinical research · 2016Article
- Preliminary study on the kidney elasticity quantification in patients with chronic kidney disease using virtual touch tissue quantification.Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society · 2015Article
- Article
- Diagnostic value of virtual touch tissue quantification for breast lesions with different size.BioMed research international · 2014Article
- Evaluation of cervical cancer detection with acoustic radiation force impulse ultrasound imaging.Experimental and therapeutic medicine · 2013Article
- Evaluation of penile erection rigidity in healthy men using virtual touch tissue quantification.Radiology and oncology · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVirtual touch tissue quantification (VTTQ) is a new, promising technique for detecting the stiffness of tissues. The aim of this study is to compare the performance of VTTQ and digital rectal examination (DRE) in discrimination between prostate cancer and benign prostatic hyperplasia (BPH). PATIENTS AND
methodsVTTQ was performed in 209 prostate nodular lesions of 107 patients with BPH and suspected prostate cancer before the prostate histopathologic examination. The shear wave velocity (SWV) at each nodular lesion was quantified by implementing an acoustic radiation force impulse (ARFI). The performance of VTTQ and DRE in discrimination between prostate cancer and BPH was compared. The diagnostic value of VTTQ and DRE for prostate cancer was evaluated in terms of the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy.
resultsProstate cancer was detected in 57 prostate nodular lesions by histopathologic examination. The SWV values (m/s) were significantly greater in prostate cancer and BPH than in normal prostate (2.37 ± 0.94, 1.98 ± 0.82 vs. 1.34 ± 0.47). The area under the receiver operating characteristic curve (AUC) for VTTQ (SWV>2.5m/s) to differentiate prostate nodules as benign hyperplasia or malignancy was 0.86, while it was 0.67 for DRE. The diagnostic sensitivity, specificity, PPV, NPV and accuracy were 71.93 %, 87.5 %, 68.33 %, 89.26 %, 83.25 %, respectively for VTTQ (SWV>2.5m/s), whereas they were 33.33 %, 81.57 %, 40.43 %, 76.54 %, 68.42 % respectively for DRE.
conclusionsVTTQ can effectively detect the stiffness of prostate nodular lesions, which has a significantly higher performance than DRE in discrimination between prostate cancer and BPH.
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