ArticleRadiology and oncology2010
Imaging findings in bisphosphonate-induced osteonecrosis of the jaws.
Article in Radiology and oncology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Prevalence of radiographic findings on jaws exposed to antiresorptive therapy: a meta-analysis.Dento maxillo facial radiology · 2019Pooled it
- Do various imaging modalities provide potential early detection and diagnosis of medication-related osteonecrosis of the jaw? A review.Dento maxillo facial radiology · 2021Review
- Spontaneous Bisphosphonate-related Osteonecrosis Associated with a Tooth that Had a Necrotic Pulp: A Case Report.Iranian endodontic journal · 2020Article
- Current Controversies on the Pathogenesis of Medication-Related Osteonecrosis of the Jaw.Dentistry journal · 2016Review
- Associations between Systemic Markers of Bone Turnover or Bone Mineral Density and Anti-Resorptive Agent-Related Osteonecrosis of the Jaw in Patients Treated with Anti-Resorptive Agents.Yonago acta medica · 2016Article
- Bisphosphonate Related Osteonecrosis of the Jaw: An Update.Journal of maxillofacial and oral surgery · 2014Review
- Nitrogen containing bisphosphonates associated osteonecrosis of the jaws: A review for past 10 year literature.Dental research journal · 2014Review
- Evolution and etiopathogenesis of bisphosphonates induced osteonecrosis of the jaw.North American journal of medical sciences · 2013Article
- Human tooth pulp anatomy visualization by 3D magnetic resonance microscopy.Radiology and oncology · 2012Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBisphosphonates are drugs used in the treatment of lytic bone metastases, multiple myeloma, hypercalcemia of malignant origin, osteoporosis, and diseases such as Paget's disease. Recently osteonecrosis of the jaw has been associated with the use of bisphosphonates. This study describes the imaging findings of bisphosphonate-associated osteonecrosis of the jaws. PATIENTS AND
methodsEleven patients, receiving bisphosphonate medication for approximately 28 months, with pain on affected side, nonhealing extraction sockets, purulent discharge and swelling in soft tissue were examined. Imaging consisted of non-contrast enhanced CT and contrast enhanced MRI. All patients underwent surgery of affected bone and histology confirmed osteonecrosis.
resultsCT scan showed osteolytic and sclerotic lesions with cortical bone destruction in all patients. The osteonecrosis was identified as delimited focal lesions with reduction of the signal on T1- weighted imaging and T2- weighted imaging. All the patients had soft-tissue involvement with enhancement in orbicular, buccinator muscle of the mouth or masticator space and adenopathy in submandibular and jugular digastric chain.
conclusionsBisphosphonate related osteonecrosis of the jaw presents a variety of imaging findings that help to determine the extent of the disease and track the progression, however they are not specific for this disease.
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