Evidence map›Paper›PMID 22932729›Full record

ArticleThe Journal of nervous and mental disease2012

Understanding the neurobiology of fear conditioning and emergence of posttraumatic stress disorder psychobiology: commentary on Blanchard et al.

Joseph A Boscarino, Charles R Figley

Abstract readComment
In one paragraph

Article in The Journal of nervous and mental disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. COVID-19 in the geriatric population.International journal of geriatric psychiatry · 2020
    Review
  3. Article
  4. Article
  5. Article
  6. The traumatology of life.The Journal of nervous and mental disease · 2012
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Joseph A BoscarinoCenter for Health Research, Geisinger Clinic, 100 N. Academy Ave., Danville, PA 17822, USA. jaboscarino@geisinger.edu
Charles R Figley

Funding

Mental Health Services in NY after WTC DisasterR01MH066403 · NIMH · NEW YORK ACADEMY OF MEDICINE · PI BOSCARINO, JOSEPH A · 2002 to 2004
$1.6M
Developing PTSD Risk Assessment Tools Using the World Trade Center Outcome StudyR21MH086317 · NIMH · GEISINGER CLINIC · PI BOSCARINO, JOSEPH A · 2009 to 2010
$437k
NIMH NIH HHS R01 MH066403NIMH NIH HHS R21 MH086317NIMH NIH HHS R21-MH-086317
6 · The paper itself

Abstract

In this article, we discuss the historical evolution of posttraumatic stress disorder (PTSD) after the Vietnam War, with a focus on an article by Blanchard, Kolb, Prins, Gates, and McCoy (J Nerv Ment Dis 179:371-373, 1991) published in this Journal in 1991 entitled Changes in Plasma Norepinephrine to Combat-Related Stimuli Among Vietnam Veterans With Posttraumatic Stress Disorder. In this commentary, we discuss the significance of this brief article and the developments in the PTSD field before, during, and after the Blanchard publication. Within this context, we discuss the eventual recognition in both the clinical and scientific fields that PTSD had a major neurobiological foundation. Finally, we examine the key implication of these discoveries from an epidemiological, a clinical, and a public health perspective.

Indexed as

Vietnam ConflictHumansStress Disorders, Post-Traumatic

Identifiers

PMID22932729
PMCPMC3432953

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.