Evidence map›Paper›PMID 22931850›Full record

ArticleEmerging infectious diseases2012

Effectiveness and timing of vaccination during school measles outbreak.

Axel Antonio Bonačić Marinović, Corien Swaan, Ole Wichmann, Jim van Steenbergen, Mirjam Kretzschmar

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Informing quarantine policy for measles control in primary school and daycare settings: insights from a simulation study, Flanders, Belgium.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Axel Antonio Bonačić MarinovićCenter for Infectious Disease Control, National Institute for Public Health and the Environment-RIVM, PO Box 1, 3720 BA Bilthoven, the Netherlands. axel.bonacic.marinovic@rivm.nl
Corien Swaan
Ole Wichmann
Jim van Steenbergen
Mirjam Kretzschmar

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite high vaccination coverage in most European countries, large community outbreaks of measles do occur, normally clustered around schools and resulting from suboptimal vaccination coverage. To determine whether or when it is worth implementing outbreak-response vaccination campaigns in schools, we used stochastic outbreak models to reproduce a public school outbreak in Germany, where no vaccination campaign was implemented. We assumed 2 scenarios covering the baseline vaccination ratio range (91.3%-94.3%) estimated for that school and computed outbreaks assuming various vaccination delays. In one scenario, reacting (i.e., implementing outbreak-response vaccination campaigns) within 12-24 days avoided large outbreaks and reacting within 50 days reduced outbreak size. In the other scenario, reacting within 6-14 days avoided large outbreaks and reacting within 40 days reduced the outbreak size. These are realistic time frames for implementing school outbreak response vaccination campaigns. High baseline vaccination ratios extended the time needed for effective response.

Indexed as

Disease OutbreaksVaccinationGermanyHumansMeaslesMeasles VaccineModels, TheoreticalRetrospective StudiesSchoolsTime FactorsMeasles Vaccine

Identifiers

PMID22931850
PMCPMC3437694

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.