Evidence map›Paper›PMID 22931069›Full record

ReviewThe American journal of drug and alcohol abuse2012

Epidemiology and etiology of substance use among American Indians and Alaska Natives: risk, protection, and implications for prevention.

Nancy Rumbaugh Whitesell, Janette Beals, Cecelia Big Crow, Christina M Mitchell, Douglas K Novins

Open access · greenAbstract readReview
In one paragraph

Review in The American journal of drug and alcohol abuse, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed, 3 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 3 syntheses or guidelines pooled it, 191 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. A Systematic Review of Trauma Interventions in Native Communities.American journal of community psychology · 2020
    Pooled it
  4. Trial
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  7. Article
  8. Article
  9. Risk factors and population attributable fraction for dementia in American Indians: The Strong Heart Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  10. Article
  11. Predictors of Opioid Misuse and Abuse Among Pregnant Women in the US.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2026
    Article
  12. E-Cigarette Use and Depression Among American Indian Adults Who Smoke.Journal of racial and ethnic health disparities · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Cultural Approaches to Promote Indigenous Mental Health: Weaving Healthy Families.Journal of ethnic & cultural diversity in social work · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Nancy Rumbaugh WhitesellCenters for American Indian and Alaska Native Health, Colorado School of Public Health, University of Colorado Denver , Aurora, CO 80045, USA. nancy.whitesell@ucdenver.edu
Janette Beals
Cecelia Big Crow
Christina M Mitchell
Douglas K Novins
Colorado School of Public Health · USNative Health · USUniversity of Colorado Denver · US

Funding

Evidence-Based Practices and Substance Abuse Treatment for Native AmericansR01DA022239 · NIDA · UNIVERSITY OF COLORADO DENVER · PI NOVINS, DOUGLAS K · 2008 to 2011
$1.4M
Partnership for Public Health Research in the Oglala Sioux TribeRC4DA029974 · NIDA · UNIVERSITY OF COLORADO DENVER · PI BEALS, JANETTE LOUISE, WHITESELL, NANCY RUMBAUGH · 2010 to 2010
$999k
NIDA NIH HHS R01 DA022239NIDA NIH HHS RC4 DA029974
6 · The paper itself

Abstract

backgroundThe epidemiology and etiology of substance use and disorder in American Indian and Alaska Native (AI/AN) communities have received increasing attention over the past 25 years and accumulating evidence provides important insights into substance use patterns in these populations. OBJECTIVES AND

methodsWe provide a descriptive sketch of the AI/AN population in the United States today, present a brief review of the literature on the epidemiology and etiology of substance use within these populations, and discuss key implications of this literature for prevention efforts. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Patterns of alcohol use and abuse in AI/AN populations are complex and vary across cultural groups, but alcohol clearly impacts both physical health and mental health within these communities. Tobacco use - and associated health consequences - is typically higher in these populations than among other US groups, although significant variation across Native communities is apparent here as with alcohol. Evidence regarding drug use and disorder is less extensive and thus less conclusive, but evidence demonstrates higher rates of use as well. Etiological explanations for substance use and disorder cut across individual characteristics (e.g., genetics) or experiences (e.g., exposure to trauma), to social contexts (e.g., family disruption), and to cultural factors (e.g., historical trauma). Protective factors likely cut across these multiple levels as well and deserve more focused attention for informing prevention efforts. The development of effective prevention strategies, built through collaboration between researchers and Native communities, drawing from the wisdom of both, is a high priority.

Indexed as

AlaskaAlcohol DrinkingCooperative BehaviorHumansIndians, North AmericanRiskSmokingSmoking PreventionSubstance-Related DisordersUnited States

Identifiers

PMID22931069
PMCPMC4436971
OpenAlexW2162353791

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.