Evidence map›Paper›PMID 22930692›Full record

ReviewMolecular endocrinology (Baltimore, Md.)2012

Minireview: applications of next-generation sequencing on studies of nuclear receptor regulation and function.

Clifford A Meyer, Qianzi Tang, X Shirley Liu

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular endocrinology (Baltimore, Md.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Clifford A MeyerDepartment of Biostatistics and Computational Biology, Harvard School of Public Health, Biostatistics and Computational Biology, 450 Brookline Street, Boston, Massachusetts 02215, USA.
Qianzi Tang
X Shirley Liu
Dana-Farber Cancer Institute · USTongji University · CN

Funding

Computational Models for Mechanisms of Global Transcription RegulationR01HG004069 · NHGRI · DANA-FARBER CANCER INST · PI LIU, XIAOLE SHIRLEY · 2006 to 2013
$3.6M
NHGRI NIH HHS HG4069NHGRI NIH HHS R01 HG004069
6 · The paper itself

Abstract

Next-generation sequencing technologies have expanded the experimental possibilities for studying the genome-wide regulation of transcription by nuclear receptors, their collaborating transcription factors, and coregulators. These technologies allow investigators to obtain abundance and DNA sequence information in a single experiment. In this review, we highlight proven and potential uses of next-generation sequencing in the study of gene regulation by nuclear receptors. We also provide suggestions on how to effectively leverage this technology in a collaborative environment.

Indexed as

High-Throughput Nucleotide SequencingAnimalsChromatin ImmunoprecipitationGene Expression ProfilingGene Expression RegulationHistonesHumansPromoter Regions, GeneticProtein BindingReceptors, Cytoplasmic and NuclearHistonesReceptors, Cytoplasmic and Nuclear

Identifiers

PMID22930692
PMCPMC3458226
OpenAlexW2032131304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.