ReviewThe Journal of pharmacology and experimental therapeutics2012
Sarcopenia: pharmacology of today and tomorrow.
Review in The Journal of pharmacology and experimental therapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The toxic effects of chloroquine and hydroxychloroquine on skeletal muscle: a systematic review and meta-analysis.Scientific reports · 2021Pooled it
- Effect of Antihypertensive and Statin Medication Use on Muscle Performance in Community-Dwelling Older Adults Performing Strength Training.Drugs & aging · 2021Trial
- Sarcopenia in Aging: Pathogenesis, Diagnosis, and Emerging Therapeutic Frontiers.Molecular imaging and biology · 2026Review
- Septin 7 interacts with Numb to preserve sarcomere structural organization and muscle contractile function.eLife · 2024Article
- Restorative effects of (+)-epicatechin in a rodent model of aging induced muscle atrophy: underlying mechanisms.Food & function · 2024Article
- SEPTIN 7 INTERACTS WITH NUMB TO PRESERVE SARCOMERE STRUCTURAL ORGANIZATION AND MUSCLE CONTRACTILE FUNCTION.bioRxiv : the preprint server for biology · 2023Article
- Article
- Biomonitoring the skeletal muscle metabolic dysfunction in knee osteoarthritis in older adults: Is Jumpstart Nutrition® Supplementation effective?Caspian journal of internal medicine · 2023Review
- Human umbilical cord-derived mesenchymal stromal cells ameliorate aging-associated skeletal muscle atrophy and dysfunction by modulating apoptosis and mitochondrial damage in SAMP10 mice.Stem cell research & therapy · 2022Article
- Numb is required for optimal contraction of skeletal muscle.Journal of cachexia, sarcopenia and muscle · 2022Article
- A simple model of immune and muscle cell crosstalk during muscle regeneration.Mathematical biosciences · 2021Article
- Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice.Stem cells international · 2021Article
- Bone Muscle Crosstalk in Spinal Cord Injuries: Pathophysiology and Implications for Patients' Quality of Life.Current osteoporosis reports · 2020Review
- Sarcopenia in patients with colorectal cancer: A comprehensive review.World journal of clinical cases · 2020Review
- Zebrafish models of sarcopenia.Disease models & mechanisms · 2020Review
- Role of Jumpstart NutritionMedical sciences (Basel, Switzerland) · 2019Article
- Nutrition, Physical Exercise, and the Prevalence of Sarcopenia in Elderly Residents in Nursing Homes in China.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Sarcopenia.Wiener medizinische Wochenschrift (1946) · 2019Review
- Circulating Irisin and Myostatin as Markers of Muscle Strength and Physical Condition in Elderly Subjects.Frontiers in physiology · 2019Article
- Characterization of a novel murine Sost ERBone research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Sarcopenia remains largely undiagnosed and undertreated because of the lack of a universally accepted definition, effective ways to measure it, and identification of the outcomes that should guide treatment efficacy. An ever-growing number of clinicians and researchers along with funding and regulatory agencies have gradually recognized that sarcopenia is a human condition that requires both prevention and treatment. In this article, we review sarcopenia and its common and less known pharmacological treatments, attempt to define sarcopenia in its broader context, and present some new ideas for potential future treatment for this devastating condition.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.