ArticleMicrobial informatics and experimentation2012
Computational genomics-proteomics and Phylogeny analysis of twenty one mycobacterial genomes (Tuberculosis & non Tuberculosis strains).
Article in Microbial informatics and experimentation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Function-based classification of hazardous biological sequences: Demonstration of a new paradigm for biohazard assessments.Frontiers in bioengineering and biotechnology · 2022Article
- The open pan-genome architecture and virulence landscape ofMicrobial genomics · 2021Article
- Pan and Core Genome Analysis of 183Antibiotics (Basel, Switzerland) · 2021Article
- Comparative Genomics of theMicroorganisms · 2020Article
- Retrospective Analysis of Archived Pyrazinamide ResistantMicroorganisms · 2019Article
- Cell-wall synthesis and ribosome maturation are co-regulated by an RNA switch in Mycobacterium tuberculosis.Nucleic acids research · 2018Article
- Comprehensive profiling of functional attributes, virulence potential and evolutionary dynamics in mycobacterial secretomes.World journal of microbiology & biotechnology · 2017Article
- Comparative pan genome analysis of oral Prevotella species implicated in periodontitis.Functional & integrative genomics · 2017Article
- Decoding the similarities and differences among mycobacterial species.PLoS neglected tropical diseases · 2017Article
- Identification of Novel Seroreactive Antigens in Johne's Disease Cattle by Using the Mycobacterium tuberculosis Protein Array.Clinical and vaccine immunology : CVI · 2017Article
- Comparative genome analyses of mycobacteria give better insights into their evolution.PloS one · 2017Article
- Phylogenetic Analysis of Prevalent Tuberculosis and Non-Tuberculosis Mycobacteria in Isfahan, Iran, Based on a 360 bp Sequence of the rpoB Gene.Jundishapur journal of microbiology · 2016Article
- Validation of qPCR Methods for the Detection of Mycobacterium in New World Animal Reservoirs.PLoS neglected tropical diseases · 2015Article
- Comparative functional pan-genome analyses to build connections between genomic dynamics and phenotypic evolution in polycyclic aromatic hydrocarbon metabolism in the genus Mycobacterium.BMC evolutionary biology · 2015Article
- Comparative whole-genome analysis of clinical isolates reveals characteristic architecture of Mycobacterium tuberculosis pangenome.PloS one · 2015Article
- A novel molecular typing method of Mycobacteria based on DNA barcoding visualization.Journal of clinical bioinformatics · 2014Article
- Comparative functional genomics and the bovine macrophage response to strains of the mycobacterium genus.Frontiers in immunology · 2014Review
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelled
backgroundThe genus Mycobacterium comprises different species, among them the most contagious and infectious bacteria. The members of the complex Mycobacterium tuberculosis are the most virulent microorganisms that have killed human and other mammals since millennia. Additionally, with the many different mycobacterial sequences available, there is a crucial need for the visualization and the simplification of their data. In this present study, we aim to highlight a comparative genome, proteome and phylogeny analysis between twenty-one mycobacterial (Tuberculosis and non tuberculosis) strains using a set of computational and bioinformatics tools (Pan and Core genome plotting, BLAST matrix and phylogeny analysis).
resultsConsiderably the result of pan and core genome Plotting demonstrated that less than 1250 Mycobacterium gene families are conserved across all species, and a total set of about 20,000 gene families within the Mycobacterium pan-genome of twenty one mycobacterial genomes.Viewing the BLAST matrix a high similarity was found among the species of the complex Mycobacterium tuberculosis and less conservation is found with other slow growing pathogenic mycobacteria.Phylogeny analysis based on both protein conservation, as well as rRNA clearly resolve known relationships between slow growing mycobacteria.
conclusionMycobacteria include important pathogenic species for human and animals and the Mycobacterium tuberculosis complex is the most cause of death of the humankind. The comparative genome analysis could provide a new insight for better controlling and preventing these diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.