Evidence map›Paper›PMID 22927962›Full record

ArticlePloS one2012

Executive functions profile in extreme eating/weight conditions: from anorexia nervosa to obesity.

Ana B Fagundo, Rafael de la Torre, Susana Jiménez-Murcia, Zaida Agüera, Roser Granero, Salomé Tárrega, Cristina Botella, Rosa Baños, Jose M Fernández-Real, Roser Rodríguez and 7 more

Abstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
93citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

93 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  19. Anandamide and 2-arachidonoylglycerol baseline plasma concentrations and their clinical correlate in gambling disorder.European psychiatry : the journal of the Association of European Psychiatrists · 2023
    Article
  20. Observational

33 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ana B FagundoDepartment of Psychiatry, University Hospital of Bellvitge-IDIBELL, Barcelona, Spain.
Rafael de la Torre
Susana Jiménez-Murcia
Zaida Agüera
Roser Granero
Salomé Tárrega
Cristina Botella
Rosa Baños
Jose M Fernández-Real
Roser Rodríguez
Laura Forcano
Gema Frühbeck
Javier Gómez-Ambrosi
Francisco J Tinahones
Jose C Fernández-García
Felipe F Casanueva
Fernando Fernández-Aranda

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtreme weight conditions (EWC) groups along a continuum may share some biological risk factors and intermediate neurocognitive phenotypes. A core cognitive trait in EWC appears to be executive dysfunction, with a focus on decision making, response inhibition and cognitive flexibility. Differences between individuals in these areas are likely to contribute to the differences in vulnerability to EWC. The aim of the study was to investigate whether there is a common pattern of executive dysfunction in EWC while comparing anorexia nervosa patients (AN), obese subjects (OB) and healthy eating/weight controls (HC).

methodsThirty five AN patients, fifty two OB and one hundred thirty seven HC were compared using the Wisconsin Card Sorting Test (WCST); Stroop Color and Word Test (SCWT); and Iowa Gambling Task (IGT). All participants were female, aged between 18 and 60 years.

resultsThere was a significant difference in IGT score (F(1.79); p<.001), with AN and OB groups showing the poorest performance compared to HC. On the WCST, AN and OB made significantly more errors than controls (F(25.73); p<.001), and had significantly fewer correct responses (F(2.71); p<.001). Post hoc analysis revealed that the two clinical groups were not significantly different from each other. Finally, OB showed a significant reduced performance in the inhibition response measured with the Stroop test (F(5.11); p<.001) compared with both AN and HC.

conclusionsThese findings suggest that EWC subjects (namely AN and OB) have similar dysfunctional executive profile that may play a role in the development and maintenance of such disorders.

Indexed as

Executive FunctionAdolescentAdultAnorexia NervosaDecision MakingFemaleHumansImpulsive BehaviorMaleMiddle AgedNeuropsychological TestsObesityYoung Adult

Identifiers

PMID22927962
PMCPMC3424186

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.