Evidence map›Paper›PMID 22927720›Full record

ReviewJournal of biomedicine & biotechnology2012

Challenging regional psoriasis and ustekinumab biotherapy: impact of the patterns of disease.

Trinh Hermanns-Lê, Enzo Berardesca, Gérald E Piérard, Marianne Lesuisse, Claudine Piérard-Franchimont

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of biomedicine & biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Treatment of nail psoriasis: common concepts and new trends.Dermatology research and practice · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Trinh Hermanns-LêDepartment of Dermatopathology, University Hospital of Liège, 4000 Liège, Belgium.
Enzo Berardesca
Gérald E Piérard
Marianne Lesuisse
Claudine Piérard-Franchimont
University of Liège · BECentre Hospitalier Régional de Huy · BECentre hospitalier régional de la Citadelle · BESan Gallicano Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In some patients, psoriasis appears refractory to many treatments, particularly when the disease is confined to some specific body regions. In this respect, palmoplantar psoriasis and palmoplantar pustulosis are possibly related conditions in their immunopathomechanisms involving Il-12, IL-23, and Th17. Nail psoriasis and scalp psoriasis are two other particular psoriasis manifestations. Accordingly, ustekinumab was tested in a few of these patients. The present paper is limited to peer-reviewed case reports. Data were not supported by bioinstrumental assessments and controlled trials. Overall, they are indicative of potential efficacy. The cost-effectiveness and the risk-benefit assessments merit further investigations.

Indexed as

Biological TherapyOrgan SpecificityAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedHumansPsoriasisUstekinumabAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedUstekinumab

Identifiers

PMID22927720
PMCPMC3425983
OpenAlexW1995046720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.