Evidence map›Paper›PMID 22927712›Full record

ArticleLearning and individual differences2012

Genetic and environmental etiologies of reading difficulties: DeFries-Fulker analysis of reading performance data from twin pairs and their nontwin siblings.

Raven L Astrom, Sally J Wadsworth, Richard K Olson, Erik G Willcutt, John C Defries

Abstract read
In one paragraph

Article in Learning and individual differences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Macular Anatomy Differs in Dyslexic Subjects.Journal of clinical medicine · 2023
    Article
  3. Article
  4. Article
  5. Multiple regression analysis of reading performance data from twin pairs with reading difficulties and nontwin siblings: the augmented model.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2012
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Raven L AstromInstitute for Behavioral Genetics, University of Colorado, Boulder, CO 80309, USA.
Sally J Wadsworth
Richard K Olson
Erik G Willcutt
John C Defries

Funding

VALIDITY OF SUBTYPES OF ADHDP50HD027802 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI ERIK G WILLCUTT · 1990 to 2026
$44.9M
Etiology and Neuropsychology of Math, Reading, ADHD, and their CovariationR01HD068728 · NICHD · UNIVERSITY OF COLORADO · PI PETRILL, STEPHEN A., WILLCUTT, ERIK G · 2011 to 2015
$3.0M
Etiology of Reading Disabilities and Comorbid ADHDR01HD047264 · NICHD · UNIVERSITY OF COLORADO AT BOULDER · PI WILLCUTT, ERIK G · 2005 to 2009
$2.7M
NICHD NIH HHS P50 HD027802NICHD NIH HHS R01 HD047264NICHD NIH HHS R01 HD068728
6 · The paper itself

Abstract

Reading performance data from 254 pairs of identical (MZ) and 420 pairs of fraternal (DZ) twins, 8.0 to 20.0 years of age, were subjected to multiple regression analyses. An extension of the DeFries-Fulker (DF) analysis (DeFries & Fulker, 1985, 1988) that facilitated inclusion of data from 303 of their nontwin siblings was employed. In addition to providing estimates of heritability, this analysis yields a test of the difference between shared environmental influences for twins versus siblings (Astrom et al., 2011). Results suggest that proband reading deficits are due substantially to genetic factors (.67 ± .07, p < .001), and that shared environmental influences are significantly higher for members of twin pairs than for those of twins and their nontwin siblings (viz., .25 versus .17, p = .02).

Identifiers

PMID22927712
PMCPMC3423974

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.