Evidence map›Paper›PMID 22926994›Full record

ReviewCurrent heart failure reports2012

Imaging the myocardial microcirculation post-myocardial infarction.

Steven K White, Derek J Hausenloy, James C Moon

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current heart failure reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Subacute cardiac rubidium-82 positron emission tomography (Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  5. Ischaemic conditioning and reperfusion injury.Nature reviews. Cardiology · 2016
    Review
  6. Article
  7. Review
  8. Intramyocardial hemorrhage: an enigma for cardiac MRI?BioMed research international · 2015
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Steven K WhiteThe Heart Hospital, London, UK. steven.white@ucl.ac.uk
Derek J Hausenloy
James C Moon
University College London · GBUniversity College Hospital at Westmoreland Street · GB

Funding

British Heart Foundation FS/10/72/28568
6 · The paper itself

Abstract

The myocardial microcirculation provides the vital pressure control and metabolic homeostasis for normal muscle function. Microvascular dysfunction is implicated in chronic cardiac disease and can signify higher risk, but its effect in acute myocardial infarction (AMI) can be profound. Modern management of AMI is focussed entirely on timely epicardial coronary patency, but as a result can leave microcirculatory devastation in its wake. The 'no-reflow' phenomenon occurs in up to 40 % of those successfully reperfused following an ST-elevation AMI (STEMI), and reflects significant microvessel injury that at its most severe involves both microvascular obstruction (MVO) and intramyocardial haemorrhage. Myocardial contrast echocardiography and cardiac magnetic resonance imaging have both led the field in establishing MVO as the prime determinant of adverse left ventricular (LV) remodeling, LV dysfunction, heart failure and increased mortality. These imaging techniques will be essential to support future research endeavours and shift focus to the maintenance of microvascular flow in AMI.

Indexed as

Cardiotonic AgentsCoronary AngiographyCoronary CirculationHumansMagnetic Resonance AngiographyMicrocirculationMyocardial InfarctionMyocardial Reperfusion InjuryPositron-Emission TomographyTomography, Emission-Computed, Single-PhotonVentricular RemodelingCardiotonic Agents

Identifiers

PMID22926994
OpenAlexW2029112024

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.