Evidence map›Paper›PMID 22926914›Full record

ArticleBiostatistics (Oxford, England)2013

Classification of patients from time-course gene expression.

Yuping Zhang, Robert Tibshirani, Ronald Davis

Abstract readComparative Study
In one paragraph

Article in Biostatistics (Oxford, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
  2. Early epitope-specific IgE antibodies are predictive of childhood peanut allergy.The Journal of allergy and clinical immunology · 2020
    Article
  3. Article
  4. Article
  5. Discriminating sample groups with multi-way data.Biostatistics (Oxford, England) · 2017
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuping ZhangStanford Genome Technology Center, Palo Alto, CA 94306, USA. yupingz@stanford.edu
Robert Tibshirani
Ronald Davis

Funding

Inflammation and the Response to InjuryU54GM062119 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI MOLDAWER, LYLE L · 2001 to 2010
$78.6M
Bridging Sustainable Distribution of TRBD Bioinformatics ResourcesR24GM102656 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI XIAO, WENZHONG · 2012 to 2014
$1.6M
NIGMS NIH HHS R24 GM102656NIGMS NIH HHS U54 GM-062119NIGMS NIH HHS U54 GM062119
6 · The paper itself

Abstract

Classifying patients into different risk groups based on their genomic measurements can help clinicians design appropriate clinical treatment plans. To produce such a classification, gene expression data were collected on a cohort of burn patients, who were monitored across multiple time points. This led us to develop a new classification method using time-course gene expressions. Our results showed that making good use of time-course information of gene expression improved the performance of classification compared with using gene expression from individual time points only. Our method is implemented into an R-package: time-course prediction analysis using microarray.

Indexed as

Data Interpretation, StatisticalModels, StatisticalBurnsGene Expression ProfilingHumansInterferon-betaMultiple SclerosisOligonucleotide Array Sequence AnalysisPredictive Value of TestsInterferon-beta

Identifiers

PMID22926914
PMCPMC3520502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.