ArticleThe European physical journal. E, Soft matter2012
Active compaction of crosslinked driven filament networks.
Article in The European physical journal. E, Soft matter, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Article
- Mobility of Molecular Motors Regulates Contractile Behaviors of Actin Networks.Biophysical journal · 2019Article
- Mechanical Properties of the Cytoskeleton and Cells.Cold Spring Harbor perspectives in biology · 2017Review
- Microscopic origins of anisotropic active stress in motor-driven nematic liquid crystals.Soft matter · 2016Article
- Active matter.The European physical journal. E, Soft matter · 2013Article
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Authors and funding
3 authors.
Funding
Abstract
The contractile ability of active materials relies on the interplay of force-exerting and force-bearing structures. However, the complexity of interactions and limited parameter control of many model systems are major obstacles in advancing our understanding of the underlying fundamental principles. To shed light on these principles we introduce and analyse a minimal reconstituted system, consisting of highly concentrated actin filaments that are crosslinked by α-actinin and actively transported in the two-dimensional geometry of a motility assay. This minimal system actively compacts and evolves into highly compact fibres that exceed the length of the individual filaments by two orders of magnitude. We identify the interplay between active transport and crosslinking to be responsible for the observed active compaction. This enables us to control the structure and the length scale of active compaction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.