ArticlePituitary2013
Evaluation of depression, quality of life and body image in patients with Cushing's disease.
Article in Pituitary, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pituitary adenomas and neuropsychological status: a systematic literature review.Neurosurgical review · 2020Pooled it
- Quality of life (QoL) impairments in patients with a pituitary adenoma: a systematic review of QoL studies.Pituitary · 2015Pooled it
- Problem-solving therapy can reduce psychological distress in patients with Cushing's disease: a randomized controlled trial.Pituitary · 2022Trial
- Very Long-Term Follow-Up of Multidimensional Health-Related Quality of Life After Endoscopic Endonasal Surgery for Pituitary Adenomas: A Prospective Cohort Study.Head & neck · 2026Article
- Changes in Body Image and Pain in Patients with Cushing Syndrome: A Predictor for Depression and Vice Versa.Journal of the Endocrine Society · 2026Article
- Sentiment Analysis of Transsphenoidal Surgery in the Cushing's Subreddit.Journal of neurological surgery. Part B, Skull base · 2025Article
- Reconstructive Liposuction for Residual Lipodystrophy After Remission of Cushing's Disease: A Case Report.Cureus · 2025Article
- Patient-reported outcomes in refractory hormone-producing pituitary adenomas: an unmet need.Pituitary · 2023Review
- Coping strategies in patients undergoing surgery treatment for pituitary tumour in China: A cross-sectional survey.Nursing open · 2023Article
- Sex differences in behavioral, cognitive and voluntary ethanol-intake effects in Dexamethasone-induced depression-like state in Wistar rat.AIMS neuroscience · 2022Article
- Patient and Provider Perspectives on Postsurgical Recovery of Cushing Syndrome.Journal of the Endocrine Society · 2021Article
- Theta oscillations in prolactinomas: Neurocognitive deficits in executive controls.NeuroImage. Clinical · 2020Article
- Psychiatric Symptoms in Cushing's Syndrome: A Systematic Review.Innovations in clinical neuroscience · 2020Review
- Clinical and biochemical manifestations of Cushing's.Pituitary · 2015Review
- Cushing's Disease - Quality of Life, Recurrence and Long-term Morbidity.European endocrinology · 2015Review
- Quality of life in Cushing's syndrome.Pituitary · 2015Review
- Body Image Disturbance in Acromegaly Patients Compared to Nonfunctioning Pituitary Adenoma Patients and Controls.International journal of endocrinology · 2015Article
- Impact of exercise on quality of life and body-self perception of patients with acromegaly.Pituitary · 2014Article
- A Study on Psychiatric Disorders, Body Image Disturbances, and Self-Esteem in Patients of Cushing's Disease.Indian journal of endocrinology and metabolismArticle
- Assessment of Anthropometric and Physical Health Indicators before and after Pituitary Surgery in Patients with Nonfunctioning Pituitary Adenomas, Acromegaly, and Cushing Disease.Indian journal of endocrinology and metabolismArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate patients with Cushing's disease (CD) who had undergone transsphenoidal surgery in terms of depression, quality of life (QoL), and perception of body image in comparison to healthy controls. Forty patients with CD and 40 healthy controls matched for demographic characteristics were included in the study. The subjects were evaluated with the Beck depression inventory (BDI), the health survey-short form (SF-36) and the multidimensional body-self relations questionnaire (MBSRQ). Subgroups of the patients with CD were formed on the basis of remission status and BDI scores. In this study, QoL in the general health category and body image were lower in the patients with CD than in the healthy subjects. However, no differences in depression scores were found between the two groups. When the CD group was evaluated according to remission rate, the mean BDI score was significantly higher in the CD patients without remission than in both the CD patients with remission and the healthy subjects (p = 0.04). However, the physical functioning, bodily pain and general health scores of the CD patients without remission on the SF-36 questionnaire were lower than in the CD patients in remission and the healthy subjects (p = 0.002, p = 0.04, p = 0.002, respectively). Fitness evaluation, health evaluation and body areas satisfaction scores of the MBSRQ were significantly different in the three groups (p = 0.003, p = 0.009 and p = 0.001, respectively). In this study, patients with CD were found to have lower QoL, lower body image perception and higher levels of depression compared to healthy controls, particularly if the disease is persistant despite surgery.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.